D-Threonine

D-Threonine 구조식 이미지
카스 번호:
632-20-2
상품명:
D-Threonine
동의어(영문):
H-D-THR-OH;D-Thr-OH;D-THREONINE, ALLO-FREE;(2R,3S)-2-AMino-3-hydroxybutanoic acid;d-threonin;D-Theronine;D-THREONINE;(r)-threonine;D-Threonine,98%;D-(+)-THREONINE
CBNumber:
CB3489099
분자식:
C4H9NO3
포뮬러 무게:
119.12
MOL 파일:
632-20-2.mol
MSDS 파일:
SDS

D-Threonine 속성

녹는점
274 °C
끓는 점
222.38°C (rough estimate)
알파
28 º (c=6, water)
밀도
1.3126 (rough estimate)
굴절률
28 ° (C=3, H2O)
저장 조건
Keep in dark place,Inert atmosphere,Room temperature
용해도
H2O: 용해성
물리적 상태
결정 또는 결정성 분말
산도 계수 (pKa)
2.19±0.10(Predicted)
색상
하얀색
수용성
녹는
Merck
9380
BRN
1721643
InChIKey
AYFVYJQAPQTCCC-STHAYSLISA-N
CAS 데이터베이스
632-20-2(CAS DataBase Reference)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xi
위험 카페고리 넘버 36/37/38
안전지침서 24/25-37/39-26
WGK 독일 3
RTECS 번호 XO8580000
HS 번호 29225000
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고 GHS hazard pictograms
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
NFPA 704
1
0 0

D-Threonine C화학적 특성, 용도, 생산

개요

D-threonine is the D-form of threonine, which is a kind of amino acids. It can be used for the preparation of enantiomerically pure 1, 3-butanediol. It is also used as the intermediate during the preparation of chiral compounds such as antibiotics. D-threonine is an effective chiral pool reagent which contains an extra stereo-center. For example, people has recently used it as the starting material for total synthesis of protected legionaminic acid.

화학적 성질

white crystalline powder or crystals

용도

D-Threonine is the unnatural isomer of L-Threonine (T405500) and is known to inhibit growth and cell wall synthesis of Mycobacterium smegmatis. D-Threonine is also used as a synthetic intermediate for the production of chiral antibiotics. It is a steroisomer of the proteinogenic amino acid L-threonine. It has the potential to treat hypostatic leg ulceration.

정의

ChEBI: D-threonine is an optically active form of threonine having D-configuration. It has a role as a Saccharomyces cerevisiae metabolite. It is a threonine and a D-alpha-amino acid. It is a conjugate base of a D-threoninium. It is a conjugate acid of a D-threoninate. It is an enantiomer of a L-threonine. It is a tautomer of a D-threonine zwitterion.

benefits

Threonine, pronounced three-uh-neen is one of nine essential amino acids your body needs to function properly. Aiding in maintaining healthy skin, teeth, collagen, elastin, and muscle tissue, it also helps with digestion, metabolism and preventing fat buildup in the liver. Threonine has been used to treat intestinal disorders and indigestion and can be used to help those suffering from depression and anxiety. Recently it has been shown to have promising sleep-promoting effects, which may prove helpful for those who have insomnia and other sleep disorders

일반 설명

D-Threonine is sweet and toxic in nature.It acts as an inhibitor of L-threonine dehydratase. L-Threonine orientations differ from D-Threonine, specifically in their angles. The L-Threonine tended to self assemble with other L-Threonine molecules while D-Threonine tended to self assemble with other D-Threonine molecules.

참고 문헌

https://www.alfa.com/zh-cn/catalog/B21177/
Ikemi, Masahisa, et al. "D-Threonine Aldolase and Its Application to D -β-Hydroxy-£-Amino Acid Synthesis." (1992).
Paek SM, et al. "Recent Advances in Substrate-Controlled Asymmetric Induction Derived from Chiral Pool α-Amino Acids for Natural Product Synthesis." Molecules 21.7(2016):951.

D-Threonine 준비 용품 및 원자재

원자재

준비 용품


D-Threonine 공급 업체

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