1,4-Dioxaspiro[4.5]decan-8-one
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1,4-Dioxaspiro[4.5]decan-8-one 속성
- 녹는점
- 70-73 °C (lit.)
- 끓는 점
- 112C
- 밀도
- 1.0887 (rough estimate)
- 굴절률
- 1.4430 (estimate)
- 저장 조건
- Keep in dark place,Inert atmosphere,Room temperature
- 용해도
- 클로로포름 & 메탄올에 용해됨
- 물리적 상태
- 결정질 분말 또는 결정
- 색상
- 흰색에서 베이지색
- 감도
- Moisture Sensitive
- BRN
- 117631
- InChI
- InChI=1S/C8H12O3/c9-7-1-3-8(4-2-7)10-5-6-11-8/h1-6H2
- InChIKey
- VKRKCBWIVLSRBJ-UHFFFAOYSA-N
- SMILES
- O1C2(CCC(=O)CC2)OCC1
- CAS 데이터베이스
- 4746-97-8(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38 | ||
| 안전지침서 | 22-24/25-36/37/39-26 | ||
| WGK 독일 | 3 | ||
| F 고인화성물질 | 8-10-21 | ||
| 위험 참고 사항 | Irritant | ||
| HS 번호 | 29110000 |
1,4-Dioxaspiro[4.5]decan-8-one C화학적 특성, 용도, 생산
화학적 성질
1,4-Dioxaspiro[4.5]decan-8-one is white to beige crystalline powder or crystals용도
1,4-Dioxaspiro[4.5]decan-8-one is used in the preparation of series of potent analgesic compounds. 1,4-Cyclohexanedione Monoethylene Acetal is also used as a building block in the synthesis of tritium labelled probes for the autoradiography study of the dopamine reuptake complex.주요 응용
1,4-Dioxaspiro[4.5]decan-8-one can be used:(1) Used in a study of microwave-assisted reductive amination.
(2) Via a novel aromatization process, this bicyclic frame can be converted into a series of 5-alkoxytryptamine derivatives including serotonin, melatonin and bufotenin.
Purification Methods
Recrystallise it from pet ether. It sublimes slowly on attempted distillation. Also purify it by dissolving it in Et2O and adding pet ether (b 60-80o) until turbid and cooling. [Gardner et al. J Am Chem Soc 22 1206 1957, Britten & Lockwood J Chem Soc Perkin Trans 1 1824 1974.] [Beilstein 19/4 V 93.]1,4-Dioxaspiro[4.5]decan-8-one 준비 용품 및 원자재
원자재
준비 용품
4,4-DIFLUOROCYCLOHEXANONE
methyl 8-oxo-1,4-dioxaspiro[4.5]decane-7-carboxylate
4-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-3-CYCLOHEXEN-1-YL]-MORPHOLINE
Pramipexole impurity 7
4-(TERT-BUTYLDIMETHYLSILYLOXY)CYCLOHEXA&
4-Methoxycyclohexanol
4-(Benzyloxy)cyclohexanone
4-Pentylcyclohexanone
INCB8761(PF-4136309)
4-Propylcyclohexanone
4-CYANOCYCLOHEXANONE CYCLIC ETHYLENE ACETAL
4-Methoxycyclohexanon
1,4-Dioxaspiro[4.5]decan-8-one 공급 업체
글로벌( 559)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Xi'an Tuochao Biotechnology Co., Ltd | +86-02988764766 +86-18092957403 |
chen.zeshan@xatuochao.com | China | 210 | 58 |
| Nanjing Hengbei Chemicals Co., Ltd. | +86-25-58393656 |
sales@hengbeichem.cn | China | 6856 | 58 |
| Nanjing Yushan Wanfang Biotechnology Co., Ltd. | +86-025-84918180 +86-18014482516 |
3552541679@qq.com | China | 1001 | 58 |
| Hebei Maison Chemical Co.,Ltd. | +8615511852758 |
sales@maisonchem.com.cn | China | 484 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15371 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21695 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 |
jack.li@time-chemicals.com | China | 1807 | 55 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| QINGDAO HONG JIN CHEMCIAL CO.,LTD. | 532-83657313 |
hjt@hong-jin.com | China | 228 | 58 |