Nandrolone phenylpropionate
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Nandrolone phenylpropionate 속성
- 녹는점
- 85-87°C
- 알파
- D +58° (chloroform)
- 끓는 점
- 487.61°C (rough estimate)
- 밀도
- 1.0140 (rough estimate)
- 굴절률
- 1.5460 (estimate)
- 저장 조건
- Controlled Substance, -20°C Freezer
- 용해도
- DMSO : 100 mg/mL (245.97 mM; Need ultrasonic)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 흰색에서 황백색까지
- InChIKey
- UBWXUGDQUBIEIZ-QNTYDACNSA-N
- SMILES
- C[C@]12CC[C@]3([H])[C@@]4([H])CCC(=O)C=C4CC[C@@]3([H])[C@]1([H])CC[C@@H]2OC(=O)CCC1C=CC=CC=1 |&1:1,4,6,16,18,22,r|
- CAS 데이터베이스
- 62-90-8(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 20/21/22-40 | ||
| 안전지침서 | 23-36 | ||
| RTECS 번호 | KG7995000 | ||
| 독성 | LD50 intraperitoneal in mouse: > 1gm/kg |
| 그림문자(GHS): |
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| 신호 어: | Danger | ||||||||||||||
| 유해·위험 문구: |
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| 예방조치문구: |
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Nandrolone phenylpropionate C화학적 특성, 용도, 생산
화학적 성질
White to Off-White Solid용도
Anabolic steroid; androgen.World Health Organization (WHO)
Nandrolone phenylpropionate, an anabolic steroid, was introduced in 1959. In 1982, low dosage preparations were prohibited in Bangladesh due to inadmissible promotion of products containing anabolic steroids for malnourished children. Higher dosage preparations of nandrolone phenylpropionate remain available in many countries, including Bangladesh, for several highly specific but limited indications that apply to patients with chronic debilitating and emaciating diseases, particularly associated with neoplasia and some types of aplastic anaemia.Synthesis
Nandrolone phenylpropionate is prepared by reacting anhydrous MeCN with a mixture of 3-phenylpropanoic acid, aryneprecursor, nandrolone CsF, K2CO3, and 18-crown-6 in 70 ?? in an oil bath.Add anhydrous MeCN (0.5 mL) to a mixture of 3-phenylpropanoic acid (30.0 mg, 0.2 mmol, 1.0 equiv), aryneprecursor (119.2 mg, 0.4 mmol, 2.0 equiv), nandrolone (82.3 mg, 0.3 mmol, 1.5 equiv), CsF (182.3 mg, 1.2 mmol, 6.0 equiv), K2CO3 (82.9 mg, 0.6 mmol, 3.0 equiv), and 18-crown-6 (158.6 mg, 0.6 mmol, 3.0 equiv). Warm the mixture to 70 ?? in an oil bath and stir at this temperature for8 hours. Remove all the volatiles directly on rotary evaporator. Purify by flash column chromatography with pet ether:EtOAc = 20:1. 1H NMR (400 MHz, CDCl3) |? 7.31-7.26(m,2H), 7.23-7.17(m,3H), 5.83 (s, lH), 4.65-4.58(m, lH), 2.95(t, J= 8.0 Hz,2H), 2.64(t, J= 8.0 Hz,2H), 2.51-2.36(m, 2H), 2.31-2.04(m, 5H), 1.86-1.79(m, 2H), 1.72-1.61 (m, 2H), 1.57-1.00(m, 8H),0.90-0.81(m, 1H), 0.79 (s, 3H)ppm.
Fig The synthetic method 1 of Nandrolone phenylpropionate
Nandrolone phenylpropionate 준비 용품 및 원자재
원자재
준비 용품
Nandrolone phenylpropionate 공급 업체
글로벌( 354)공급 업체
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