Berberine hydrochloride
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Berberine hydrochloride 속성
- 녹는점
- 204-206 °C (dec.)
- 저장 조건
- Inert atmosphere,2-8°C
- 용해도
- 메탄올 에 용해됨
- 물리적 상태
- 노란색 가루
- 색상 색인 번호
- 75160
- 색상
- 황색 분말
- 수용성
- 냉수에 용해됨
- BRN
- 3836585
- 안정성
- 흡습성
- InChI
- InChI=1S/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1
- InChIKey
- VKJGBAJNNALVAV-UHFFFAOYSA-M
- SMILES
- C12C=C3C(C(OC)=C(OC)C=C3)=C[N+]=1CCC1=CC3=C(OCO3)C=C21.[Cl-]
- CAS 데이터베이스
- 633-65-8
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 20/21/22-36/37/38 | ||
| 안전지침서 | 24/25-36-26 | ||
| 유엔번호(UN No.) | 1544 | ||
| WGK 독일 | 2 | ||
| RTECS 번호 | DR9866400 | ||
| F 고인화성물질 | 3-10 | ||
| TSCA | Yes | ||
| 위험 등급 | 6.1(b) | ||
| 포장분류 | III | ||
| HS 번호 | 29349990 | ||
| 독성 | LD50 orl-rat: >15 g/kg KSRNAM 8,654,74 |
| 그림문자(GHS): |
 
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| 신호 어: | Danger | |||||||||||||||||||||||||||||||||||||||||||||||||
| 유해·위험 문구: |
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| 예방조치문구: |
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Berberine hydrochloride C화학적 특성, 용도, 생산
화학적 성질
yellow crystalline powder용도
Berberine hydrochloride: antiarrhythmic, alpha2 agonist, anticonvulsant, antiinflammatory, antibacterial, antifungal, antitrypanosomal, antineoplastic, immunostimulant일반 설명
A highly potent and selective oxysterol EBI2 (GPR183) agonist (Kd) = 450 pM in a saturation binding assay, and EC50 = 140 pM over EC50 = 2.1 nM for its enantiomer, 7β,25-OHC, in a GTP-γS binding assay). Dose-dependently suppresses forskolin-induced cAMP accumulation in an EBI2-expressing SK-N-MC/CRE-β-galactosidase cell line (IC50 = 2 nM), but not in control cells. Stimulates migration of LPS-activated spleen B-cells and anti-CD3/CD28-activated CD4+ T-cells in a dose-dependent manner. In addition, pharmacological inhibition of its biosynthesis in vivo by Clotrimazole, a CYP7B1inhibitor, promotes the migration of adoptively transferred pre-activated B cells to the T/B boundary, mimicking the phenotype of pre-activated B cells in EBI2-deficient mice.Safety Profile
Poison by intraperitoneal route.Slightly toxic by ingestion. Mutation data reported. Whenheated to decomposition it emits toxic vapors of NOx andCl-.Purification Methods
Berberine chloride crystallises from water to give the dihydrate. The anhydrous salt may be obtained by recrystallisation from EtOH/Et2O, wash the crystals with Et2O and dry them in a vacuum. The iodide has m 250o(dec) (from EtOH). [Perkin J Chem Soc 113 503 1918, Kametani et al. J Chem Soc(C) 2036 1969, Beilstein 27 I 515, 27 II 567.]Clinical claims and research
People most commonly use berberine for diabetes, high levels of cholesterol or other fats in the blood, and high blood pressure. It is also used for burns, canker sores, liver disease, and many other conditions but there is no good scientific evidence to support many of these uses.Berberine hydrochloride 준비 용품 및 원자재
원자재
준비 용품
Berberine hydrochloride 공급 업체
글로벌( 637)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Chengdu ChenLv Herb Co.,Ltd | +undefined13608205856 |
maryextract@126.com | China | 127 | 58 |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 |
info@konochemical.com | China | 2995 | 58 |
| XINGTAI XINGJIU NEW MATERIAL TECHNOLOGY CO., LTD | +8617731987558 |
xingjiu@xingjiubiotech.com | China | 990 | 58 |
| Wuhan ShuEr Biology Technology Co.,Ltd | +86-15629032529 |
excellentsuppliers@shuerbio.com | China | 897 | 58 |
| Bonerge(Hunan) Lifescience Co., Ltd. | +86-731-82791134 +86-18801900056 |
hank.h@bonerge.com | China | 30 | 58 |
| Shaanxi LonierHerb Bio Technology Co Ltd | +86-86-+86-86-029-87551862 +8617702909819 |
sales006@ingredients-lonier.com | China | 2596 | 58 |
| BINBO BIOLOGICAL CO.,LTD | +8618629063126 |
info@binbobiological.com | China | 259 | 58 |
| XI'AN TIANGUANGYUAN BIOTECH CO., LTD. | +86-029-86333380 18829239519 |
sales06@tgybio.com | China | 961 | 58 |
| ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD | +8619155187336 |
shengzhikai3@shengzhikai.com | China | 38 | 58 |
| shandong perfect biotechnology co.ltd | +86-53169958659; +8618596095638 |
sales@sdperfect.com | China | 294 | 58 |
Berberine hydrochloride 관련 검색:
염화칼슘 염화나트륨 염화칼륨 염화콜린 염화 암모늄 케르세틴 염화 폴리비닐 3,4-다이하이드로-2,5,7,8-테트라메틸-2-(4,8,12-트라이메틸트 라이데실)-2H-벤조피란-6-올 메틸 옥시레인, 중합체 ,함유 옥시레인, 에테르 ,함유 (1,2-에탄딜- 디니트리로)테트라키스(프로판올)
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