JAK3 INHIBITOR VI
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JAK3 INHIBITOR VI 속성
- 저장 조건
- +2C to +8C
- 물리적 상태
- 노란색 고체
안전
JAK3 INHIBITOR VI C화학적 특성, 용도, 생산
일반 설명
A cell-permeable, potent, and reversible inhibitor of Janus kinase 3 (JAK3) (IC50 = 27 nM). Reported to bind to the enzyme active site and prevent IL-2-induced phosphorylation of JAK3 and STAT5. Also reported to inhibit IL-2-induced cell proliferation (IC50 = 760 nM for murine CTLL cells and 250 nM for human T-cells). Shown to alleviate oxazolone-induced ear edema in mice with an efficacy comparable to Dexamethasone (Cat. No. 265005) and displays ~16-fold greater selectivity over JAK2.Biochem/physiol Actions
Cell permeable: yesJAK3 INHIBITOR VI 준비 용품 및 원자재
원자재
준비 용품
JAK3 INHIBITOR VI 공급 업체
글로벌( 8)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 |
klq@cw-bio.com | China | 3444 | 55 |
Beijing Biocreative Technology Co., Ltd. | 15522676233 |
3007606172@qq.com | China | 1249 | 58 |