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paraflutizide

paraflutizide 구조식 이미지

카스 번호:: 1580-83-2

상품명:: paraflutizide

동의어(영문):: LD-3612;Paraflutizida;paraflutizide;6-Chloro-3-(p-fluorobenzyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide;6-chloro-3-(4-fluorobenzyl)-1,1-diketo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide;6-chloro-3-[(4-fluorophenyl)methyl]-1,1-dioxo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide;2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-[(4-fluorophenyl)methyl]-3,4-dihydro-, 1,1-dioxide

CBNumber:: CB3875049

분자식:: C14H13ClFN3O4S2

포뮬러 무게:: 405.85

MOL 파일:: 1580-83-2.mol

속성

안전

용도

공급 업체 8

paraflutizide 속성

녹는점: 238-240°

끓는 점: 636.2±65.0 °C(Predicted)

밀도: 1.571±0.06 g/cm3(Predicted)

산도 계수 (pKa): 8.66±0.40(Predicted)

안전

독성	LD50 oral in mouse: > 10gm/kg

paraflutizide C화학적 특성, 용도, 생산

Originator

Paraflutizide, Shanghai Lansheng

Manufacturing Process

A mixture of 5.0 g (0.0357 g/mol) of ρ-fluorophenylethyl alcohol, 2.0 g (0.007 g/mol) of 5-chloro-2,4-disulphamylaniline, 2.0 g (0.0068 g/mol) of potassium bichromate and 15 ml of concentrated hydrochloric acid (0.176 g/mol) and 25 ml of water is heated under reflux for 1 h. The mixture is allowed to cool, and 15 ml of ether are added to separate the excess of ρ-fluorophenylethyl alcohol. The aqueous layer is decanted and frozen for 2 h and the precipitate is separated, washed with water and dried in vacuum over phosphoric anhydride. There are collected 1.35 g (yield 47.5%) of the 1,1-dioxide of 3-ρfluorophenyl-methyl-7-sulphamyl-6-chloro-3,4-dihydrobenzo-1,2,4-thiadiazine, which when recrystallised from 30 ml of 50% alcohol on "Norit" active carbon takes the form of a white crystalline substance, melting point is 239°C.

Therapeutic Function

Diuretic

paraflutizide 준비 용품 및 원자재

원자재

염산 중크롬산 칼륨 5-클로로-2-메틸-4-이소티아졸린-3-온

준비 용품

paraflutizide 공급 업체

글로벌( 8)공급 업체

공급자	전화	이메일	국가	제품 수	이점
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd	15229059051	1027@dideu.com	China	9926	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24131	58

paraflutizide 관련 검색:

히드로클로로티아지드 Chlorothiazide 4-Amino-6-chlorobenzene-1,3-disulfonamide 2-amino-N-propylbenzenesulfonamide ethiazide BENZYLHYDROCHLOROTHIAZIDE paraflutizide