라코사미드
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라코사미드 속성
- 녹는점
- 141-143?C
- 알파
- D23 +16.0° (c = 1 in CH3OH)
- 끓는 점
- 536.4±50.0 °C(Predicted)
- 밀도
- 1.120±0.06 g/cm3(Predicted)
- 인화점
- 2℃
- 저장 조건
- Refrigerator
- 용해도
- DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 2 mg/ml
- 물리적 상태
- 결정성 고체
- 산도 계수 (pKa)
- 14.19±0.46(Predicted)
- InChIKey
- VPPJLAIAVCUEMN-GFCCVEGCSA-N
- CAS 데이터베이스
- 175481-36-4
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | F,Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 11-20/21/22-36 | ||
| 안전지침서 | 16-26-36/37 | ||
| 유엔번호(UN No.) | UN 1648 3 / PGII | ||
| WGK 독일 | 2 | ||
| HS 번호 | 2924296000 |
라코사미드 C화학적 특성, 용도, 생산
개요
Although epilepsy is a neurological disorder with varying etiology and severity, the common feature is unprovoked, recurring seizures. Whether classified as generalized, involving both cerebral hemispheres, or partial with only localized portions of brain participation at onset, effective treatment relies on accurate assessment of syndrome type to optimally decrease the frequency, duration, and severity of seizures. The latest weapon against partial onset epilepsy is lacosamide, formerly known as harkoseride and erlosamide. The data also indicate that lacosamide binds to collapsing response mediator protein 2 (CRMP2); CRMP2 is involved in neuronal differentiation, control of axonal outgrowth, and possibly epileptogenesis. Furthermore, lacosamide is heralded as having a dual mode of action as it has also displayed efficacy against diabetic neuropathy, possibly as a result of stabilization of neuronal hyperexcitability. Currently,lacosamide is approved as adjunctive treatment of partial onset seizures in patients 17 years or older and is in development as a monotherapy for epilepsy and for neuropathic pain.화학적 성질
White to Off-White Solid용도
A potent anticonvulsant.라코사미드 준비 용품 및 원자재
원자재
준비 용품
라코사미드 공급 업체
글로벌( 478)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5993 | 58 |
| Changzhou Rokechem Technology Co., Ltd. | 18758118018 |
sales001@rokechem.com | China | 255 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 |
Mandy@hangyubiotech.com | China | 11013 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Nanjing Gold Pharmaceutical Technology Co. Ltd. | 025-84209270 15906146951 |
CHINA | 115 | 55 | |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21695 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9350 | 55 |
| Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ |
sales03@shyrchem.com | CHINA | 738 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
라코사미드 관련 검색:
프로피온아미드
Febuxostat
LacosaMide iMpurity
(S)-2-Acetamido-N-benzyl-3-methoxypropanamide
2-(Acetylamino)-N-(phenylmethyl)-2-propenamide
(R)-O-Acetyl-LacosaMide
Benzylamine hydrochloride
(R)-2-amino-N-benzyl-3-methoxypropanamide
Desmethyl Lacosamide
Lacosamide EP impurity I
Lacosamide EP impurity G
Lacosamide EP impurity B
Lacosamide EP impurity J
Lacosamide EP impurity E
Lacosamide EP impurity F
Lacosamide EP impurity A
Avoparcin
LACOSAMIDE