눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
P337+P313
눈에 대한 자극이 지속되면 의학적인 조치· 조언를 구하시오.
NFPA 704
1
1
0
1,8-다이클로로안트라퀴논 C화학적 특성, 용도, 생산
용도
1,8-Dichloroanthraquinone is a reagent in the preparation of anthraquinones, which has antitumor activities. It is used as primary and secondary intermediate.
Safety Profile
An eye irritant. When
heated to decomposition it emits toxic
fumes of Cl-.
Synthesis
1,8-Dichloroanthraquinone is prepared by the reaction of 1-chloroanthracene-9,10-dione and 2-chloroanthracene-9,10-dione. The steps are as follows: 80 L of the mother liquors obtained according to Example 1a and 40 L of the mother liquors obtained according to Example 1b are combined in a 250 L enamel kettle and heated to 100℃. 12 L of a 10% strength aqueous sodium chlorate solution are fed in at a uniform rate at this temperature in the course of 4 hours, while stirring at 30 - 40 revolutions per minute with an anchor stitter. The mixture is stirred for a further 2 hours at 100℃. and filtered at 80℃. through a filter press, the material on the filter is washed with hot water until the filtrate gives a neutral reaction and the filter cake is dried. 1,8-dichloroanthraquinone are obtained.
