플로레틴
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플로레틴 속성
- 녹는점
- ~260 °C
- 끓는 점
- 337.26°C (rough estimate)
- 밀도
- 1.1827 (rough estimate)
- 굴절률
- 1.573-1.575
- 저장 조건
- 2-8°C
- 용해도
- 아세토니트릴(약간), 메탄올(약간)에 용해됨
- 산도 계수 (pKa)
- 7.16±0.40(Predicted)
- 물리적 상태
- 가루
- 색상
- 흰색에서 베이지색
- 냄새
- 냄새 없는
- 수용성
- 녹는
- Merck
- 14,7326
- JECFA Number
- 2022
- BRN
- 1887240
- InChIKey
- VGEREEWJJVICBM-UHFFFAOYSA-N
- LogP
- 3.50
- CAS 데이터베이스
- 60-82-2(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38 | ||
| 안전지침서 | 37/39-26-36 | ||
| WGK 독일 | 3 | ||
| F 고인화성물질 | 3-10 | ||
| 위험 등급 | IRRITANT | ||
| HS 번호 | 29145090 | ||
| 기존화학 물질 | KE-20817 |
플로레틴 C화학적 특성, 용도, 생산
화학적 성질
Crystalline Solid용도
Phloretin has been used:- to study its effect on the 2-[N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)amino]-2-deoxy-d-glucose (2-NBDG) and 2-[N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)amino]-2-deoxy-l-glucose (2-NBDLG) uptake
- to incubate microvesicles in order to inhibit GLUT1 (glucose transporter 1)-mediated transport in radioactive ligand up-take assay
- as a component of KRH buffer to stop glucose uptake by trophoblast cells in vitro
용도
As glucose transport inhibitor, Phloretin can inhibits protein kinase C and has been shown to inhibit the entry of five enveloped viruses into human fibroblasts.정의
ChEBI: Phloretin is a member of the class of dihydrochalcones that is dihydrochalcone substituted by hydroxy groups at positions 4, 2', 4' and 6'. It has a role as a plant metabolite and an antineoplastic agent. It is functionally related to a dihydrochalcone.일반 설명
Phloretin is a dihydrochalcone flavonoid with antioxidant activity usually found in apples and apple-derived products. It is extensively used for peroxynitrite scavenging and the inhibition of lipid peroxidation. It has been found to inhibit the growth of several cancer cells and induce apoptosis of B16 melanoma and HL60 human leukemia cells.Purification Methods
Crystallise phloretin from aqueous EtOH. [Zemplen & Bognár Chem Ber 75 1040 1942, Zemplén Chem Ber 76 386 1943, Beilstein 8 IV 3518.]플로레틴 준비 용품 및 원자재
원자재
준비 용품
플로레틴 공급 업체
글로벌( 456)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| XI AN SGONEK BIOLOGICAL TECHNOLOGY CO., LTD | 15202951039 |
jason@sgonekbio.com | China | 268 | 58 |
| Bonerge(Hunan) Lifescience Co., Ltd. | +86-731-82791134 +86-18801900056 |
hank.h@bonerge.com | China | 30 | 58 |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 |
qinhe02@xaltbio.com | China | 1000 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 7332 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21695 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 |
sales@sdzschem.com | China | 2931 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 |
sales@biopurify.com | China | 3424 | 58 |