퍼몰린 C화학적 특성, 용도, 생산
화학적 성질
White Solid
용도
A CNS stimulant. Controlled Substance
정의
ChEBI: A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted by an amino group at position 2 and by a phenyl group at position 5. A central nervous system stimulant, it was used to treat hyperactivity disorders
in children, but withdrawn from use following reports of serious hepatotoxicity.
World Health Organization (WHO)
Pemoline was introduced in 1975 for the treatment of attentiondeficit
disorder. Because of its central stimulating effects it has also been used in
weight control in combination with anorectic agents, laxatives.
일반 설명
Pemoline, 2-amino-5-phenyl-4(5H)-oxazolone (Cylert), hasa unique structure.
The compound is described as having an overall effect onthe CNS like that of methylphenidate. Pemoline requires 3to 4 weeks of administration, however, to take effect. A partialexplanation for the delayed effect may be that one of theactions of the agent, as observed in rats, is to increase therate of synthesis of DA.
생물학적 활성
Long-acting central stimulant that induces self-injurious behavior in rats. Acts as an indirect monoamine agonist.
퍼몰린 준비 용품 및 원자재
원자재
준비 용품
