13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1

13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1 구조식 이미지
카스 번호:
5094-14-4
상품명:
13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1
동의어(영문):
U 21002;13,14-dihydro-15-keto PGE1;CDUVSQMTLOYKTR-ZHALLVOQSA-N;13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1;9,15-dioxo-11α-hydroxy-prostan-1-oic acid;9,15-DIOXO-11ALPHA-HYDROXY-PROSTAN-1-OIC ACID;Prostan-1-oic acid, 11-hydroxy-9,15-dioxo-, (11α)-;15-Keto Prostaglandin E0 DISCONTINUED, OFFER K202056
CBNumber:
CB4190392
분자식:
C20H34O5
포뮬러 무게:
354.49
MOL 파일:
5094-14-4.mol

13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1 속성

끓는 점
537.2±35.0 °C(Predicted)
밀도
1.072±0.06 g/cm3(Predicted)
저장 조건
-20°C Freezer, Under inert atmosphere
용해도
DMSO (약간 용해됨), 메탄올 (약간 용해됨), THF (약간 용해됨)
물리적 상태
기름
산도 계수 (pKa)
4.77±0.10(Predicted)
색상
진한 노란색

안전

13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1 C화학적 특성, 용도, 생산

개요

13,14-dihydro-15-keto Prostaglandin E1 (PGE1) is a metabolite of PGE1 with much reduced biological activity. Steady state plasma concentrations are about 10 pg/ml. 13,14-dihydro-15-keto PGE1 is a weak inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 54 and 200 μM, respectively, compared to PGE1 which has an IC50 of 40 nM.

용도

15-Keto Prostaglandin E0 is a metabolite of Prostaglandin E1 (P838600) and has been shown to induce arterial thromboresistance in experimental animals and in man, but with several magnitudes higher concentrations than Prostaglandin E1. 15-Keto Prostaglandin E0 is also used as the active ingredient in compositions used for the treatment of external secretion disorders.

13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1 준비 용품 및 원자재

원자재

준비 용품


13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1 공급 업체

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