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Isochlorogenic acid C

Isochlorogenic acid C 구조식 이미지

카스 번호:: 57378-72-0

상품명:: Isochlorogenic acid C

동의어(영문):: 4,5-Dicaffeoylquinic acid;3,4-O-Dicaffeoylquinic acid;Isochlorogenic acid C;Isochlorogenic acid C(4,5');4,5-Dicaffeoylquinic acid, >99%;Isochlorogenic acid C USP/EP/BP;1β,5α-Dihydroxy-3β,4β-bis[3-(3,4-dihydroxyphenyl)propenoyloxy]cyclohexanecarboxylic acid;(1R)-1,3β-Dihydroxy-4α,5α-bis[3-(3,4-dihydroxyphenyl)acryloyloxy]-1β-cyclohexanecarboxylic acid;(1R,3R,4S,5R)-3,4-Bis((3-(3,4-dihydroxyphenyl)acryloyl)oxy)-1,5-dihydroxycyclohexanecarboxylic acid;(1R,3R,4S,5R)-1,5-Dihydroxy-3,4-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1-cyclohexanecarboxylicaci

CBNumber:: CB42201548

분자식:: C25H24O12

포뮬러 무게:: 516.45

MOL 파일:: 57378-72-0.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 151

Isochlorogenic acid C 속성

끓는 점: 810.8±65.0 °C(Predicted)

밀도: 1?+-.0.1 g/cm3(Predicted)

저장 조건: Inert atmosphere,Store in freezer, under -20°C

용해도: DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:5): 0.16 mg/ml; DMSO: 5 mg/ml

물리적 상태: 고체

산도 계수 (pKa): 3.70±0.50(Predicted)

안전

WGK 독일	3

Isochlorogenic acid C C화학적 특성, 용도, 생산

개요

4,5-Dicaffeoylquinic acid (4,5-DCQA) is a polyphenol originally isolated from G. fagetorum and G. pseudomollugo that has diverse biological activities, including anti-HIV replication, antioxidative, anti-inflammatory, and anti-melanogenic properties. It inhibits HIV-1 integrase 3'' end processing, 3’ end joining, and disintegration with IC₅₀ values of 0.13, 0.24, and 0.3 μg/ml, respectively. It also inhibits HIV-1 replication in MT-2 T lymphoblastoid cells with an EC₅₀ value of 2 μg/ml. 4,5-DCQA scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay (IC₅₀ = 19.8 μM) and inhibits superoxide production in human neutrophils activated by N-formyl-Met-Leu-Phe (fMLF; ) and cytochalasin B (; IC₅₀ = 1.49 μM). It decreases prostaglandin E₂ (PGE₂; ) production in LPS-stimulated U937 cells when used at concentrations of 5 and 10 μg/ml but increases it when used at 200 μg/ml and increases production of TNF-α at concentrations ranging from 5 to 200 μg/ml. It inhibits the synthesis of MCP3 in U937 cells. 4,5-DCQA (25 μM) inhibits melanogenesis by 84% and decreases the levels of proteins involved in melanin biosynthesis, including tyrosinase, TRP-1, DCT, and MITF in B16F1 murine melanocytes.

용도

4,5-Dicaffeoylquinic Acid is a selective inhibitor of human immunodeficiency virus type 1 integrase.

Isochlorogenic acid C 준비 용품 및 원자재

원자재

준비 용품

Isochlorogenic acid C 공급 업체

글로벌( 151)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3424	58
Shanghai Standard Technology Co., Ltd.	18502101150	ft-sales@nature-standard.com	CHINA	1923	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-519-519-85557386	marketing1@neostarunited.com	China	8349	58
Wuhan ChemNorm Biotech Co.,Ltd.	+86-27-8439 4403 18971486879	sales@chemnorm.com	CHINA	2935	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10326	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418671	sales@tnjchem.com	China	34572	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29118	58
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9702	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58

Isochlorogenic acid C 관련 검색:

Isochlorogenic acid C BAVACHININ A epiberberine Isochlorogenic Acid B glaucocalyxin A Taxifolin Isochlorogenic acid A Isoastilbin Fluorescein isothiocyanate Isocitric acid trisodium salt (E,E)-3,5-Di-O-caffeoylquinic acid CAFTARIC ACID Cryptochlorogenic acid Chlorogenic acid CYNARIN 1,3,5-Tricaffeoylquinic acid 1-Caffeoylquinic acid 2,3,4,5-Tetracaffeoyl-D-Glucaric acid