Tavaborole
|
|
Tavaborole 속성
- 녹는점
- 120-122℃
- 끓는 점
- 230.8±50.0 °C(Predicted)
- 밀도
- 1.28±0.1 g/cm3(Predicted)
- 저장 조건
- -20°C
- 용해도
- DMSO(약간 용해됨), 메탄올(약간 용해됨)
- 산도 계수 (pKa)
- 6.81±0.20(Predicted)
- 물리적 상태
- 가루
- 색상
- 흰색에서 베이지색
- 안정성
- 흡습성
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
HS 번호 | 2934999090 | ||
---|---|---|---|
유해 물질 데이터 | 174671-46-6(Hazardous Substances Data) |
Tavaborole C화학적 특성, 용도, 생산
개요
Tavaborole (Kerydin®), discovered and developed by Anacor, was approved by the US FDA in July 2014. Tavaborole, topical solution, 5% is an oxaborole antifungal indicated for the treatment of onychomycosis of the toenails due to Trichophyton rubrum or Trichophyton mentagrophytes. The mechanism of action of tavaborole is inhibition of fungal protein synthesis, which inhibits an aminoacyl-transfer ribonucleic acid synthetase.용도
Tavaborole is a topical treatment of toenail onychomycosis.정의
ChEBI: A member of the class of benzoxaboroles that is 1,3-dihydro-1-hydroxy-2,1-benzoxaborole substituted at position 5 by a fluoro group. A topical antifungal agent used for the treatment of onychomycosis (fungal infection of the toenails and fingernails).일반 설명
Tavaborole is a boron-based pharmaceutical agent. It has broad-spectrum oxaborole antifungal activity. Due to its low molecular weight, it facilitates maximal nail plate penetration than its predecessors.Tavaborole 준비 용품 및 원자재
원자재
5-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde
Benzene, 1-bromo-2-[(1-ethoxyethoxy)methyl]-4-fluoro-
Reaxys ID: 10668384
4-Fluoro-2-methylphenylboronic acid
(4-Fluoro-2-(hydroxyMethyl)phenyl)boronic acid
2-bromo-5-fluoro-[1-(methoxymethoxy)methyl]benzene
보릭산트리이소프로필에스테르
물
2-Bromo-5-fluorobenzyl alcohol
준비 용품
Tavaborole 공급 업체
글로벌( 208)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15371 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21695 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 |
admin@nexconn.com | China | 10248 | 58 |
Accela ChemBio Inc. | (+1)-858-699-3322 |
info@accelachem.com | United States | 19965 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
WinWin Chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 |
sales@win-winchemical.com | China | 13854 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 |
sales@hzclap.com | CHINA | 6313 | 58 |
AFINE CHEMICALS LIMITED | 0571-85134551 |
info@afinechem.com | CHINA | 15377 | 58 |
Tavaborole 관련 검색:
6-aMinobenzo[c][1,2]oxaborol-1(3H)-ol
Vaniprevir
2-(Hydroxymethyl)-6-methoxyphenylboronic acid dehydrate
(2-HYDROXYMETHYL-5-NITRO)BENZENEBORONIC ACID DEHYDRATE
2,1-Benzoxaborole,1,3-dihydro-1-hydroxy-6-Methoxy
benzo[c][1,2]oxaborole-1,6(3H)-diol
6-chlorobenzo[c][1,2]oxaborol-1(3H)-ol
7-fluorobenzo[c][1,2]oxaborol-1(3H)-ol
5-(TRIFLUOROMETHYL)BENZO[C][1,2]OXABOROL-1(3H)-OL
6-FLUOROBENZO[C][1,2]OXABOROL-1(3H)-OL
4-aminobenzo[c][1,2]oxaborol-1(3H)-ol
5-aminobenzo[c][1,2]oxaborol-1(3H)-ol
ISOINDOLIN-4-OL HYDROCHLORIDE
7-aminobenzo[c][1,2]oxaborol-1-(3H)-ol
1-Hydroxy-2,1-benzoxaborolane
4-Fluoro-2-methylphenylboronic acid
Tavaborole