니모투주맙
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니모투주맙 속성
안전
니모투주맙 C화학적 특성, 용도, 생산
개요
Overexpression of epidermal growth factor receptor (EGFR), a transmembrane receptor tyrosine kinase, is prevalent in malignant tumors of epithelial origin and is especially common in breast, head and neck, colon, and lung cancer. With EGFR overexpression, prognosis is poor due to associated tumor invasion, metastasis, enhanced angiogenesis, and resistance to chemotherapy; thus, modulation of EGFR-mediated signaling is an attractive target for intervention. Small-molecule kinase inhibitors (gefitinib and erlotinib) and a monoclonal antibody (cetuximab) specific for EGFR are in clinical evaluation, but treatment cessation due to development of severe acne-like rash is common with these EGFR antagonists. Notably, nimotuzumab, a humanized form of the murine IgG2a monoclonal antibody that has been launched in India for treatment of head and neck cancers overexpressing EGFR, demonstrates clinical efficacy devoid of the rash toxicity. .Originator
Center for Molecular Immunology (Cuba)상표명
BioMab EFGR, Theraloc니모투주맙 준비 용품 및 원자재
원자재
준비 용품
니모투주맙 공급 업체
글로벌( 16)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 |
support@targetmol.com | United States | 19973 | 58 |
LGM Pharma | 1-(800)-881-8210 |
inquiries@lgmpharma.com | United States | 2127 | 70 |
NCE Biomedical Co.,Ltd. | 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988 |
China | 1494 | 55 | |
SPIRO PHARMA | |
eric_feng1954@126.com | China | 9254 | 55 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9707 | 58 |
ShangHai Biochempartner Co.,Ltd | 17754423994 17754423994 |
2853530910@QQ.com | China | 8014 | 62 |
Guangzhou Hongyuan Chemical Co.,Ltd | 15817493340 |
981810490@qq.com | China | 1565 | 58 |
Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 |
422450190@qq.com | China | 10351 | 58 |
Abmole Bioscience Inc. | 021-50967598 02150967598 |
sales@abmole.cn | China | 4495 | 58 |
Jiangxi ravel Biotechnology Co.,Ltd | 400-880-2824; 13184580281 |
hj@ruiweier.cn | China | 2711 | 58 |
니모투주맙 관련 검색:
Follicle stimulating hormone
Secukinumab
Daratumumab
OMALIZUMAB
Dulaglutide
Trastuzumab emtansine
Ranibizumab
palivizumab
Immunoglobulin G4,anti-(human integrin R4) (human-mouse monoclonal AN100226 c4-chain),disulfide with human-mouse monoclonal AN100226 light chain,dimer
Eculizumab
Aflibercept
abciximab
Matuzumab
ticilimumab tremelimumab
CNTO 148
Vedolizumab
Avelumab
belimumab