피페라진 시트르산
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피페라진 시트르산 속성
- 녹는점
- 183-187℃
- 끓는 점
- 208℃[at 101 325 Pa]
- 밀도
- 0.741[at 20℃]
- 증기압
- 56.928Pa
- 저장 조건
- Inert atmosphere,Room Temperature
- 용해도
- DMSO에 용해됨
- 물리적 상태
- powder to crystal
- 색상
- 흰색에서 거의 흰색
- 수용성
- 54g/L at 24℃
- Merck
- 14,7464
- LogP
- -1.15
- CAS 데이터베이스
- 144-29-6(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
피페라진 시트르산 C화학적 특성, 용도, 생산
개요
Piperazine is an organic compound that consists of a six-membered ring containing two opposing nitrogen atoms. First used as a solvent for uric acid, the use of piperazine as an anthelmintic agent was first introduced in 1953. Upon entry into the systemic circulation, the drug is partly oxidized and partly eliminated as an unchanged compound. Outside the body, piperazine has a remarkable power to dissolve uric acid and producing a soluble urate, but in clinical experience it has not proved equally successful. Piperazine was first introduced as an anthelmintic in 1953. Piperazine compounds mediate their anthelmintic action by generally paralyzing parasites, allowing the host body to easily remove or expel the invading organism.화학적 성질
Piperazine citrate is a white, crystalline powder, with not more than a slight odor. It is soluble in water, and insoluble in alcohol and in ether.용도
Piperazine Citrate is an anthelmintic agent used in the treatment of parasitic infections. Also used in the reduction of blood pressure.Indications
Used as alternative treatment for ascariasis caused by Ascaris lumbricoides (roundworm) and enterobiasis (oxyuriasis) caused by Enterobius vermicularis (pinworm). It is also used to treat partial intestinal obstruction by the common roundworm, a condition primarily occurring in children.Mechanism of action
Piperazine is a GABA receptor agonist. Piperzine binds directly and selectively to muscle membrane GABA receptors, presumably causing hyperpolarization of nerve endings, resulting in flaccid paralysis of the worm. While the worm is paralyzed, it is dislodged from the intestinal lumen and expelled live from the body by normal intestinal peristalsis.Pharmacokinetics
Piperazine is an anthelminthic especially useful in the treatment of partial intestinal obstruction caused by Ascaris worms, which is a condition primarily seen in children. Piperazine hydrate and piperazine citrate are the main anthelminthic piperazines.피페라진 시트르산 준비 용품 및 원자재
원자재
준비 용품
피페라진 시트르산 공급 업체
글로벌( 230)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Masteam Bio-tech Co., Ltd. | +86-15200345168 +86-15200345168 |
bruce.lei@masteam.com | CHINA | 153 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12446 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 |
sales1@chuanghaibio.com | China | 5882 | 58 |
Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618740459177 |
sarah@tnjone.com | China | 1143 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21667 | 55 |
Chembon Pharmaceutical Co., Ltd. | +86-28-8425-2981 |
CHINA | 724 | 55 | |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29888 | 58 |
SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 |
sales@sdzschem.com | China | 2931 | 58 |
Jinan Shengqi pharmaceutical Co,Ltd | 86+18663751872 |
christine@shengqipharm.com | CHINA | 491 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8820 | 58 |
피페라진 시트르산 관련 검색:
소듐 하이드로젠사이트레이트 세스퀴하이드레이트 피페라진 시트르산 시트르산(구연산)
Trisodium citrate dihydrate
Disodium citrate
Sodium citrate
CITRIC ACID ISOPROPYL ESTER
Calcium citrate
Potassium Citrate
Sodium ferrous citrate
Triethyl citrate
Ammonium citrate dibasic
BETAINE CITRATE
POTASSIUM DIHYDROGEN CITRATE
AMMONIUM BISMUTH CITRATE
Maropitant citrate hydrate
MAGNESIUM CITRATE
2-Hydroxy-1,2,3-propanetricarboxylic acid/ammonia,(1:x)