5-Hydroxy-3,4-dihydroquinolin-2(1H)-one

5-Hydroxy-3,4-dihydroquinolin-2(1H)-one 구조식 이미지
카스 번호:
30389-33-4
상품명:
5-Hydroxy-3,4-dihydroquinolin-2(1H)-one
동의어(영문):
5-Hydroxy-3,4-dihydroquinolin-2(1H)-one;5-Hydroxy-3,4-dihydrocarbostyryl;Carteolol EP Impurity B;5-HYDROXY-3;Carteolol int;Carteolol Impurity 2;Carteolol Intermediate;Aripiprazole impurity 7;Aripiprazole Impurity 14;Brexpiprazole Impurity 70
CBNumber:
CB4259600
분자식:
C9H9NO2
포뮬러 무게:
163.17
MOL 파일:
30389-33-4.mol

5-Hydroxy-3,4-dihydroquinolin-2(1H)-one 속성

녹는점
225-227°C
끓는 점
381.2±42.0 °C(Predicted)
밀도
1.282±0.06 g/cm3(Predicted)
저장 조건
Inert atmosphere,Room Temperature
용해도
DMSO(약간 용해됨), 메탄올(약간 용해됨)
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
9.63±0.20(Predicted)
색상
흰색에서 황백색까지
CAS 데이터베이스
30389-33-4(CAS DataBase Reference)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xi
HS 번호 2933499090
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고 GHS hazard pictograms
예방조치문구:
P260 분진·흄·가스·미스트·증기·...·스프레이를 흡입하지 마시오.
P271 옥외 또는 환기가 잘 되는 곳에서만 취급하시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.

5-Hydroxy-3,4-dihydroquinolin-2(1H)-one C화학적 특성, 용도, 생산

화학적 성질

Off-white Solid

용도

Carteolol (C184450) metabolite.

Synthesis

To a 100 ml three-necked flask were added 3,4,7,8-tetrahydro-2,5 (1 H, 6Η) -quinoline dione (0.02 mol) and cyclohexane (25 ml). After stirring to dissolve in the ice bath for 10min, slowly add a dropwise N-bromosuccinimide (0.03mol) in cyclohexane (5ml), and reflux for 3h at the end of the dropwise addition. After completion of the reaction by TLC, cool down to room temperature. Water was added (the amount was 0.7 times the volume of the reactant), and the mixture was allowed to stand with stirring. The aqueous layer was extracted with ethyl acetate (1 × the volume of the aqueous layer 4 times), and the organic layers were combined. Anhydrous sulfuric acid Calcium was dried and filtered, the filtrate was evaporated to remove the solvent, and the residue was dried to give an off-white solid as a 5-Hydroxy-3,4-dihydroquinolin-2(1H)-one (Yield 92.7percent).

5-Hydroxy-3,4-dihydroquinolin-2(1H)-one 준비 용품 및 원자재

원자재

준비 용품


5-Hydroxy-3,4-dihydroquinolin-2(1H)-one 공급 업체

글로벌( 205)공급 업체
공급자 전화 이메일 국가 제품 수 이점
HangZhou RunYan Pharma Technology Co.,LTD.
+86-88660901 +86-18112526015
sales@runyanpharma.com China 326 58
Zibo Hangyu Biotechnology Development Co., Ltd
+86-0533-2185556 +8617865335152
Mandy@hangyubiotech.com China 11013 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886
info@dakenam.com China 15928 58
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714
fandachem@gmail.com China 9348 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3012 60
career henan chemical co
+86-0371-86658258
sales@coreychem.com China 29914 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28180 58
Jinan Finer Chemical Co., Ltd
+86-531-88989536 +86-15508631887
sales@finerchem.com China 2967 58
Accela ChemBio Inc.
(+1)-858-699-3322
info@accelachem.com United States 19965 58
Hubei xin bonus chemical co. LTD
86-13657291602
linda@hubeijusheng.com CHINA 22968 58

5-Hydroxy-3,4-dihydroquinolin-2(1H)-one 관련 검색:

Copyright 2019 © ChemicalBook. All rights reserved