(S)-3-aMino-1-hydroxy-3,4-dihydroquinolin-2(1H)-one hydrochloride
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(S)-3-aMino-1-hydroxy-3,4-dihydroquinolin-2(1H)-one hydrochloride 속성
- 저장 조건
- room temp
- 용해도
- H2O: 용해성20mg/mL, 투명
- 물리적 상태
- 가루
- 색상
- 흰색에서 베이지색
- 수용성
- Water: 22 mg/ml
안전
(S)-3-aMino-1-hydroxy-3,4-dihydroquinolin-2(1H)-one hydrochloride C화학적 특성, 용도, 생산
Biochem/physiol Actions
PF-04859989 is a brain-penetrable irreversible inhibitor of kynurenine amino transferase II (KAT II), the enzyme responsible for most of the brain synthesis of kynurenic acid, which has been implicated in several psychiatric and neurological disorders, including schizophrenia and bipolar disorder, and thought to impair cognitive function. PF-04859989 has IC50 values of 23 nM for hKAT II and 263 nM for rKAT II. PF-04859989 is ~1000-fold selective for KAT II over human KAT I, KAT III, and KAT IV. PF-04859989 prevented ketamine-induced disruption of performance in memory tasks in both rodents and nonhuman primates.(S)-3-aMino-1-hydroxy-3,4-dihydroquinolin-2(1H)-one hydrochloride 준비 용품 및 원자재
원자재
준비 용품
(S)-3-aMino-1-hydroxy-3,4-dihydroquinolin-2(1H)-one hydrochloride 공급 업체
글로벌( 20)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Labnetwork lnc. | +86-27-50766799 +8618062016861 |
contact@labnetwork.com | China | 19994 | 58 |
Aladdin Scientific | +1-833-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 18521732826; |
market@aladdin-e.com | China | 25015 | 65 |
Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
ShangHai Angti Biotechnology Co., Ltd. | 13764913901 |
info@angtibio.com | China | 4484 | 55 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9709 | 58 |
Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 4009686088 |
3193328036@qq.com | China | 29797 | 68 |
Tianjin heowns Biochemical Technology Co., Ltd. | 400-6387771-6037 18920794737 |
sales@heowns.com | China | 20499 | 60 |
Jiangsu aikang biomedical research and development co., LTD | 025-66110311 13155353615 |
qzhang@aikonchem.com | China | 15527 | 58 |