ChemicalBook >제품 카탈로그 >PF 04995274

PF 04995274

PF 04995274 구조식 이미지

카스 번호:: 1331782-27-4

상품명:: PF 04995274

동의어(영문):: PF 04995274;PF04995274;PF 04995274;PF-04995274 >=98% (HPLC);4-[[4-[[4-[(3R)-oxolan-3-yl]oxy-1,2-benzoxazol-3-yl]oxymethyl]piperidin-1-yl]methyl]oxan-4-ol;2H-Pyran-4-ol, tetrahydro-4-[[4-[[[4-[[(3R)-tetrahydro-3-furanyl]oxy]-1,2-benzisoxazol-3-yl]oxy]methyl]-1-piperidinyl]methyl]-;Inhibitor,5-HT4,5-hydroxytryptamine Receptor,behavior,Alzheimer′s disease,PF-04995274,inhibit,PF04995274,Serotonin Receptor,5-HT Receptor,Stress-induced,PF 04995274,depressive-like

CBNumber:: CB42668576

분자식:: C23H32N2O6

포뮬러 무게:: 432.51

MOL 파일:: 1331782-27-4.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 36

PF 04995274 속성

저장 조건: Store at -20°C

용해도: DMSO:20.0(Max Conc. mg/mL);46.2(Max Conc. mM)

물리적 상태: 결정성 고체

안전

PF 04995274 C화학적 특성, 용도, 생산

개요

PF-04995274 is a partial agonist of the serotonin (5-HT) receptor subtypes 5-HT_4A, 5-HT_4B, 5-HT_4D, and 5-HT_4E (K_is = 0.36, 0.46, 0.15, and 0.32 nM, respectively, in a radioligand binding assay). It increases cAMP levels in HEK293 cells expressing 5-HT_4A, 5-HT_4B, 5-HT_4D, and 5-HT_4E receptors (EC₅₀s = 0.47, 0.36, 0.37, and 0.26 nM, respectively, for the human recombinant receptors). PF-04995274 decreases scopolamine-induced increases in the distance traveled in the Morris water maze in rats when administered at a dose of 0.032 mg/kg.

PF 04995274 준비 용품 및 원자재

원자재

준비 용품

PF 04995274 공급 업체

글로벌( 36)공급 업체

공급자	전화	이메일	국가	제품 수	이점
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3136	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Shanghai Boyle Chemical Co., Ltd.		sales@boylechem.com	China	2923	55
Taizhou Tongxin Bio-Tech Co., Ltd	0523-18601685-898 18652728585	sales@allyrise.com	China	2743	60
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4121	55
Taizhou Ruixin Chemical Co., Ltd.	0576-89085261 15867635987	jasonhu09@163.com	China	442	50
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58

PF 04995274 관련 검색:

PF-06282999 PF 4618433 PF-06650833 PF-6260933 5-PyriMidinecarboxaMide, 4-[(2-Methylpropyl)aMino]-N-(phenylMethyl)-2-[4-[(tetrahydro-2H-pyran-3-yl)Methyl]-1-piperazinyl]- PF-01247324 PNU 100480 PF 05175157 PF-06882961 PF-5190457 PF-05212384 [(3R)-1-[2-[1-(4-Chloro-1H-pyrazol-1-yl)cyclopropyl]-3H-imidazo[4,5-b]pyridin-5-yl]-3-piperidinyl]-1-pyrrolidinyl-methanone methanesulfonate PF-04691502 PF 477736 PF-06700841-TsOH PF 573228 PF-3084014 PF 3644022