Fmoc-Gly-OH

Fmoc-Gly-OH 구조식 이미지
카스 번호:
29022-11-5
상품명:
Fmoc-Gly-OH
동의어(영문):
FMOC-GLY-OH;FMOC-GLY;FMOC-L-GLY;Fmoc-g;Fmoc-GL;FMOC-L-GLY-OH;FMOC-L-GLYCINE;FMoc-DL-Glycine;N-(fluoren-9-ylmethoxycarbonyl)glycine;npc14692
CBNumber:
CB4288480
분자식:
C17H15NO4
포뮬러 무게:
297.31
MOL 파일:
29022-11-5.mol
MSDS 파일:
SDS

Fmoc-Gly-OH 속성

녹는점
174-175 °C(lit.)
끓는 점
438.82°C (rough estimate)
밀도
1.1671 (rough estimate)
굴절률
1.4500 (estimate)
저장 조건
2-8°C
용해도
almost transparency in Methanol
산도 계수 (pKa)
3.89±0.10(Predicted)
물리적 상태
가루
색상
하얀색
BRN
2163967
InChI
InChI=1S/C17H15NO4/c19-16(20)9-18-17(21)22-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15H,9-10H2,(H,18,21)(H,19,20)
InChIKey
NDKDFTQNXLHCGO-UHFFFAOYSA-N
SMILES
C(O)(=O)CNC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
CAS 데이터베이스
29022-11-5(CAS DataBase Reference)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xi
위험 카페고리 넘버 36/37/38
안전지침서 24/25-36-26
WGK 독일 3
HS 번호 29242995
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고 GHS hazard pictograms
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
NFPA 704
0
0 0

Fmoc-Gly-OH MSDS


Fmoc-Gly-OH

Fmoc-Gly-OH C화학적 특성, 용도, 생산

화학적 성질

white to light yellow crystal powde

용도

Fmoc-Gly-OH is an N-Fmoc-protected form of Glycine (G615990). Glycine is a nonessential amino acid that acts as an inhibitory neyrotransmitter in the vertebrate central nervous system. Glycine also posesses cytoprotective against oxidant damage in the kidney.

제조 방법

Glycine (Gly) (0.5 g, 6.66 mmol) was dissolved in 10% NaCO3 (14 ml) under stirring in a 50-ml flask. To the resulting solution, which had been put into an ice bath, 9-fluorenylmethoxycarbonyl chloride (Fmoc-Cl) (1.72 g, 6.66 mmol) in dioxane (12 ml) was gradually added. The reaction mixture was stirred at room temperature for 4 hours. Then added water (150 ml) to the mixture. The aqueous phase layer was separated from the reaction mixture and stripped with ether three times (75 ml×3). The stripped aqueous layer was acidified with 2N HCl aqueous solution to a pH=2, followed by extraction with ethyl acetate three times (75 ml×3). The organic phase layer was recovered and concentrated to obtain crude product of 1.70 g. The crude product was recrystallized in a mixed solvent of ethyl acetate hexane=1:2 (30 ml), and white solid denoted as Fmoc-Gly-OH was obtained after filtration at a reduced pressure.
Fmoc-Gly-OH

일반 설명

The product number for this product was previously 04-12-1001.

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Fmoc-Gly-OH 준비 용품 및 원자재

원자재

준비 용품


Fmoc-Gly-OH 공급 업체

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