Lafutidine
|
|
Lafutidine 속성
- 녹는점
- 92.7-94.9°
- 끓는 점
- 704.2±60.0 °C(Predicted)
- 밀도
- 1.252±0.06 g/cm3(Predicted)
- 저장 조건
- Sealed in dry,Store in freezer, under -20°C
- 수용성
- 물에 불용성
- 용해도
- DMF:5.0(Max Conc. mg/mL);11.59(Max Conc. mM)
DMSO:48.67(Max Conc. mg/mL);112.77(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:10):0.09(Max Conc. mg/mL);0.21(Max Conc. mM)
Ethanol:9.0(Max Conc. mg/mL);20.86(Max Conc. mM)
- 물리적 상태
- powder to crystal
- 산도 계수 (pKa)
- 13.13±0.46(Predicted)
- 색상
- White to Orange to Green
- CAS 데이터베이스
- 118288-08-7(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 안전지침서 | 24/25 | ||
|---|---|---|---|
| HS 번호 | 29349990 |
Lafutidine C화학적 특성, 용도, 생산
개요
Lafutidine was launched in Japan for the treatment of gastritis, reflux oesophagitis and peptic ulcers. It can be prepared in eight steps from 4-(2-tetrahydropyranyloxy)-2(Z)-butenl- ol. Lafutidine is a potent and longer-acting H2 antagonist compared to other marketed compounds of its class such as cimetidine and famotidine. In contrast to other commercially available H2 antagonists, lafutidine also exerts a gastroprotective action probably via capsaicin-sensitive afferent nerves. It was clinically effective in the treatment of nonsteroidal antiinflammatory drug-induced ulcer in patients refractory to existing antiulcer agents.용도
Lafutidine, a newly developed histamine H(2)-receptor antagonist, inhibits gastric acid secretionLafutidine 준비 용품 및 원자재
원자재
Pyridine, 4-(1-piperidinylmethyl)-2-[[(2Z)-4-[(tetrahydro-2H-pyran-2-yl)oxy]-2-buten-1-yl]oxy]-
118289-23-9
2-(4-((4-(1,3-dioxolan-2-yl)pyridin-2-yl)oxy)but-2-en-1-yl)isoindoline-1,3-dione
118287-95-9
118289-22-8
4-((4-(1,3-dioxolan-2-yl)pyridin-2-yl)oxy)but-2-en-1-ol
4-(1,3-dioxolan-2-yl)-2-((4-((tetrahydro-2H-pyran-2-yl)oxy)but-2-en-1-yl)oxy)pyridine
피페리딘
준비 용품
Lafutidine 공급 업체
글로벌( 306)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Jinan Shengqi pharmaceutical Co,Ltd | 86+18663751872 |
christine@shengqipharm.com | CHINA | 491 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| HubeiwidelychemicaltechnologyCo.,Ltd | 18627774460 |
faith@widelychemical.com | CHINA | 742 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
| Shanghai Yingrui Biopharma Co.,Ltd | 21-33585366 |
export01@shyrchem.com | CHINA | 1320 | 58 |
Lafutidine 관련 검색:
라니티딘 FAMOTI디NE 2-메틸-2-부텐 아세트아마이드 푸란
Omeprazole
Lafutidine
N-{4-[4-(PIPERIDINOMETHYL)PYRIDYL-2-OXY]-CIS-2-BUTENE}PHTHALIMIDE MALEIC ACID(INTERMEDIATE FOR LAFUTIDINE)
LACTITOL MONOHYDRATE,LACTITOL H2O,D-LACTITOL MONOHYDRATE,LACTITOL MONOHYDRATE 99%
p-Nitrophenyl 2-(Furfurylsulfinyl)acetate
4-[4-(Piperidinomethyl)pyridyl-2-oxy]-cis-2-butenamine
2-ALLYLOXYPYRIDINE
LACTITOL
(Z)-4-[(TETRAHYDRO-2H-PYRAN-2-YL)OXY]-2-BUTEN-1-OL (PREPARATION FOR LAFUTIDINE)
Lomerizine
2(1H)-Pyridinone,4-(aminomethyl)-(9CI)
2-((FURAN-2-YL)METHYLSULFINYL)-N-((Z)-4-HYDROXYBUT-2-ENYL)ACETAMIDE
N-(PYRIDIN-4-YLMETHYL)BUTAN-1-AMINE