펠로디핀
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펠로디핀 속성
- 녹는점
- 142-145°C
- 끓는 점
- 471.5±45.0 °C(Predicted)
- 밀도
- 1.3506 (rough estimate)
- 굴절률
- 1.6500 (estimate)
- 저장 조건
- 2-8°C
- 용해도
- DMSO: 28mg/mL
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 2.73±0.70(Predicted)
- 색상
- 연노랑
- 수용성
- 불용성
- 안정성
- 제공된 대로 구매일로부터 1년 동안 안정적입니다. DMSO 또는 에탄올 용액은 -20°에서 최대 3개월 동안 보관할 수 있습니다.
- InChI
- InChI=1S/C18H19Cl2NO4/c1-5-25-18(23)14-10(3)21-9(2)13(17(22)24-4)15(14)11-7-6-8-12(19)16(11)20/h6-8,15,21H,5H2,1-4H3
- InChIKey
- RZTAMFZIAATZDJ-UHFFFAOYSA-N
- SMILES
- C1(C)NC(C)=C(C(OC)=O)C(C2=CC=CC(Cl)=C2Cl)C=1C(OCC)=O
- CAS 데이터베이스
- 72509-76-3(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
펠로디핀 MSDS
4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinecarboxylic acid ethyl methyl ester
펠로디핀 C화학적 특성, 용도, 생산
개요
Felodipine is a vasodilatory calcium antagonist with a high degree of vascular selectivity. It is currently indicated for use only in hypertension, either as monotherapy or in conjunction with diuretics or beta blockers.화학적 성질
White or Light Yellow Crystalline Powder용도
Felodipine is used as a dihydropyridine calcium channel blocker. It displays high vascular selectivity; lowers arterial blood pressure without altering cardiac contractility. Antihypertensive.정의
ChEBI: The mixed (methyl, ethyl) diester of 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium-channel blocker, it lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth m scle in arteriolar resistance vessels. It is used in the management of hypertension and angina pectoris.일반 설명
Felodipine, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethylmethyl ester (Plendil), is a second-generation dihydropyridinechannel blocker of the nifedipine type. It is more selectivefor vascular smooth muscle than for myocardial tissueand serves as an effective vasodilator.생물학적 활성
L-type Ca 2+ channel blocker that is selective over N-, R-, P/Q- and T-type channels. Displays high vascular selectivity; lowers arterial blood pressure without altering cardiac contractility. Antihypertensive.Clinical Use
Felodipine is used inthe treatment of angina and mild-to-moderate essential hypertension.Felodipine, like most of the dihydropyridines,exhibits a high degree of protein binding and has a half-liferanging from 10 to 18 hours.펠로디핀 준비 용품 및 원자재
원자재
3-아미노크로톤산메틸
메틸 아세토아세테이트
3-Amino-2-butenoic acid ethyl ester
2,3-디클로로벤즈알데히드
이소프로필알코올
염산
NeMadipine B
Felodipine 3,5-DiMethyl Ester
준비 용품
펠로디핀 공급 업체
글로벌( 505)공급 업체
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| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
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| career henan chemical co | +86-0371-86658258 |
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| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 |
sales@amoychem.com | China | 6387 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |