헤스페레틴
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헤스페레틴 속성
- 녹는점
- 230-232°C
- 끓는 점
- 363.32°C (rough estimate)
- 밀도
- 1.2514 (rough estimate)
- 굴절률
- -4 ° (C=1.8, EtOH)
- 저장 조건
- Inert atmosphere,Room Temperature
- 용해도
- DMSO(약간 용해됨), 메탄올(약간 용해됨)
- 산도 계수 (pKa)
- 7.49±0.40(Predicted)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 흰색에서 연한 노란색
- 수용성
- 물(일부), 묽은 알칼리 및 에탄올(50mg/ml)에 용해됩니다.
- Merck
- 14,4670
- BRN
- 309850
- InChIKey
- AIONOLUJZLIMTK-AWEZNQCLSA-N
- LogP
- 2.90
- CAS 데이터베이스
- 520-33-2(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38 | ||
| 안전지침서 | 26-36/37/39-27-37 | ||
| WGK 독일 | 3 | ||
| HS 번호 | 29329990 |
헤스페레틴 C화학적 특성, 용도, 생산
개요
Hesperetin is a flavonoid that has been found in citrus fruits and has diverse biological activities. It reduces ApoB protein levels, ACAT2 expression, and LDL degradation in HepG2 cells when used at a concentrations ranging from 10 to 200 μM. Hesperetin inhibits IgG-induced β-hexosaminidase release from RBL-2H3 cells (IC50 = 0.099 mg/ml). It inhibits LPS-induced nitric oxide (NO) production and reduces levels of inducible nitric oxide synthase (iNOS), IL-6, and IL-1β in BV-2 microglial cells. Hesperetin (5 mg/kg) inhibits passive cutaneous anaphylaxis in mice. It reduces body weight loss, colon shortening, and ulcer severity in a mouse model of TNBS-induced ulcerative colitis. Hesperetin reduces cortical and hippocampal neuronal apoptosis and increases time spent in the target quadrant in the Morris water maze in a mouse model of LPS-induced neuronal inflammation.화학적 성질
Beige to Light Brown Crystalline Solid용도
(±)-Hesperetin is an antioxidant flavonoid. Induces G1-phase cell cycle arrest. Anti-inflammatory. (±)-Hesperetin suppresses NF-κB activation. Reduces cholesterol biosynthesis. Inhibits lipid peroxidation. Neuroprotective against neuronal oxidative damage.정의
ChEBI: Hesperetin is a trihydroxyflavanone having the three hydroxy gropus located at the 3'-, 5- and 7-positions and an additional methoxy substituent at the 4'-position. It has a role as an antioxidant, an antineoplastic agent and a plant metabolite. It is a monomethoxyflavanone, a trihydroxyflavanone, a member of 3'-hydroxyflavanones and a member of 4'-methoxyflavanones. It is a conjugate acid of a hesperetin(1-).Purification Methods
Crystallise it from EtOAc or ethanol. The natural S(-) form crystallises from EtOH and has m 216-218o and [] D -37.6o (c 2, EtOH). Note that C2 is chiral. [Beilstein 18 II 204, 18 III/IV 3215, 18/5 V 214.]헤스페레틴 준비 용품 및 원자재
원자재
준비 용품
헤스페레틴 공급 업체
글로벌( 424)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Changsha Staherb Natural Ingredients Co., Ltd. | +86-0731-84213302 +8618374838656 |
sales@staherb.cn | China | 1025 | 58 |
| BINBO BIOLOGICAL CO.,LTD | +8618629063126 |
info@binbobiological.com | China | 290 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 |
sales@biopurify.com | China | 3424 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 |
info@accelachem.com | United States | 19965 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 |
sales@amoychem.com | China | 6387 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 |
sales@pioneerbiotech.com | China | 3000 | 58 |
헤스페레틴 관련 검색:
루테올린 시트르산 페루라산 레스베라트롤 케르세틴 디하이드레이트 비타민 P
HESPERETIN-7-NEOHESPERIDOSIDE hplc,Neohesperidin，Hesperetin 7-neohesperidoside,HESPERETIN-7-NEOHESPERIDOSIDE,HESPERETIN-7-O-NEOHESPERIDOSIDE
Paeoniflorin
Naringin
(+/-)-HESPERETIN,HESPERETIN
HESPERETIN LAURATE
4'-METHOXYFLAVANONE
4'-METHOXYFLAVANONE
hesperetin 5-O-glucoside
HESPERETIN, [3H(G)]
HESPERETIN CHALCONE
HESPERETIN DIHYDROCHALCONE
HESPERETIN DIHYDROCHALCONE(RG)