4BP-TQS

4BP-TQS 구조식 이미지
카스 번호:
360791-49-7
상품명:
4BP-TQS
동의어(영문):
4BP-TQS;4BP-TQS >=98% (HPLC);3H-Cyclopenta[c]quinoline-8-sulfonamide, 4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-;4BP TQS,allosteric agonist,transmembrane site,Inhibitor,α7 nAChR,inhibit,Nicotinic acetylcholine receptors,4BPTQS,nAChR,4BP-TQS
CBNumber:
CB43067530
분자식:
C18H17BrN2O2S
포뮬러 무게:
405.31
MOL 파일:
360791-49-7.mol
MSDS 파일:
SDS

4BP-TQS 속성

녹는점
>202°C (dec.)
끓는 점
566.2±60.0 °C(Predicted)
밀도
1.505±0.06 g/cm3(Predicted)
저장 조건
-20°C
용해도
DMSO(약간 용해됨), 메탄올(약간 용해됨, 초음파처리)
산도 계수 (pKa)
10.21±0.40(Predicted)
물리적 상태
가루
색상
흰색에서 베이지색

안전

4BP-TQS C화학적 특성, 용도, 생산

Biochem/physiol Actions

4BP-TQS is an atypical agonist of a7-nAChR that binds to the receptor in an intrasubunit cavity, and activates the channel via a mechanism that is distinct from conventional agonists. Maximal activation of a7-nAChR by 4BP-TQS is eight fold greater than activation by a maximum dose of acetylcholine (Ach), and 4BP-TQS can poteniate an EC10 concentration of ACh to invoke a response that is 540-fold higher than the maximal dose of ACh alone.

4BP-TQS 준비 용품 및 원자재

원자재

준비 용품


4BP-TQS 공급 업체

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