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N-desalkylflurazepam

N-desalkylflurazepam 구조식 이미지

카스 번호:: 2886-65-9

상품명:: N-desalkylflurazepam

동의어(영문):: DESALKYLFLURAZEPAM;NORFLUDIAZEPAM;N-desallkylflurazepam;FlurazepaM Related CoMpound F;cm7116;ro5-3367;sch17514;RO 5-3367;nor-Flurazepam;norflutoprazepam

CBNumber:: CB4316060

분자식:: C15H10ClFN2O

포뮬러 무게:: 288.7

MOL 파일:: 2886-65-9.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 204

N-desalkylflurazepam 속성

녹는점: 204-206°C

끓는 점: 454.0±45.0 °C(Predicted)

밀도: 1.39±0.1 g/cm3(Predicted)

인화점: 9℃

저장 조건: Sealed in dry,Room Temperature

용해도: 클로로포름(약간 용해됨), 메탄올(약간 용해됨)

물리적 상태: A neat solid

산도 계수 (pKa): 11.55±0.70(Predicted)

InChI: InChI=1S/C15H10ClFN2O/c16-9-5-6-13-11(7-9)15(18-8-14(20)19-13)10-3-1-2-4-12(10)17/h1-7H,8H2,(H,19,20)

InChIKey: UVCOILFBWYKHHB-UHFFFAOYSA-N

SMILES: N1C2=CC=C(Cl)C=C2C(C2=CC=CC=C2F)=NCC1=O

CAS 데이터베이스: 2886-65-9(CAS DataBase Reference)

NIST: Norfludiazepam(2886-65-9)

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

위험품 표기	F,T
위험 카페고리 넘버	11-23/24/25-39/23/24/25
안전지침서	22-24/25-45-36/37-16-7
유엔번호(UN No.)	UN1230 - class 3 - PG 2 - Methanol, solution
WGK 독일	2
RTECS 번호	DF2370100
HS 번호	2933997500

그림문자(GHS):

신호 어:

Warning

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	그림 문자	P- 코드
H336	졸음 또는 현기증을 일으킬 수 있음	특정표적장기 독성 물질(1회 노출);마취작용	구분 3	경고		P261, P271, P304+P340, P312,P403+P233, P405, P501

예방조치문구:

P261	분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P271	옥외 또는 환기가 잘 되는 곳에서만 취급하시오.
P403+P233	용기는 환기가 잘 되는 곳에 단단히 밀폐하여 저장하시오.
P405	밀봉하여 저장하시오.
P501	...에 내용물 / 용기를 폐기 하시오.

NFPA 704

	0
2		0

N-desalkylflurazepam C화학적 특성, 용도, 생산

개요

Desalkylflurazepam (Item No. 18484) is an analytical reference material that is structurally categorized as a benzodiazepine. It is an active metabolite of several benzodiazepines, including flurazepam , flutoprazepam, fludiazepam, midazolam, and quazepam. Desalkylflurazepam inhibits L-type voltage-gated calcium channels (Ca_v; IC₅₀s = 55 and 37 μM for Ca_v1.2 and 1.3, respectively) by positively modulating GABA_A receptors. It can be detected in urine, serum, and meconium by LC-MS/MS. This product is intended for research and forensic applications.

화학적 성질

Light Yellow Solid

용도

The major human metabolite of flurazepam. This is a controlled drug precursor therefore a liscence may be required for purchase

일반 설명

N-Desalkylflurazepam (also known as norflurazepam, 2886-65-9) is a benzodiazepine analog and an active metabolite of several other benzodiazepine drugs including flurazepam, flutoprazepam, fludiazepam, midazolam, flutazolam, quazepam, and ethyl loflazepate. It is long-acting, prone to accumulation, and binds unselectively to the various benzodiazepine receptor subtypes. It has been sold as a designer drug from 2016 onward.

Mode of action

N-Desalkylflurazepam is a benzodiazepine analog and an active metabolite of several other benzodiazepine drugs including flurazepam, flutoprazepam, fludiazepam, midazolam, flutazolam, quazepam, and ethyl loflazepate. It is long-acting, prone to accumulation, and binds unselectively to the various benzodiazepine receptor subtypes. It has been sold as a designer drug from 2016 onward.

N-desalkylflurazepam 준비 용품 및 원자재

원자재

7-Chloro-1,3-dihydro-5-(2-fluorophenyl)-2-nitromethyl-ene-2H-1,4-benzodiazepine 2-bromo-4'-chloro-2'-(o-fluorobenzoyl)acetanilide 2-chloro-N-[4-chloro-2-(2-fluorobenzoyl)phenyl]acetamide BOC-Glycine

준비 용품

Flualprazolam 2-Amino-5-chloro-2'-fluorobenzophenone 4-Imidazolidinone, 1,1'-methylenebis[3-[4-chloro-2-(o-fluorobenzoyl)phenyl]- (7CI,8CI) Midazolam [7-CHLORO-5-(2-FLUORO-PHENYL)-3H-BENZO[E][1,4]DIAZEPIN-2-YL]-METHYL-AMINE

N-desalkylflurazepam 공급 업체

글로벌( 204)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hebei Miaoyin Technology Co.,Ltd	+86-17367732028 +86-17367732028	kathy@hbyinsheng.com	China	3582	58
Dorne Chemical Technology co. LTD	+86-13583358881 +86-18560316533	Ethan@dornechem.com	China	294	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
Anhui Yiao New Material Technology Co., Ltd	+86-199-55145978 +8619955145978	sales8@anhuiyiao.com	China	253	58
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	994	58
Shandong Hanjiang Chemical Co., Ltd	+86-0533-2066820 +8618369939125	hanson@sdhanjiang.com	China	1527	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9348	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58

N-desalkylflurazepam 관련 검색:

히드로클로로티아지드 부틸디페닐클로로실란 에피클로로하이드린 1,8-디아자비사이클로[5.4.0]운덴센-7 트리틸클로라이드 페닐히드라진 디하이드로미르세놀 클로로아세트산 클로로디플루오르메탄 CHLOROPHENYLSILANE 97 PHENYL VALERATE Chlorodimethylphenylsilane 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one FLURAZEPAM DIHYDROCHLORIDE Doxefazepam Proflazepam Elfazepam FLURAZEPAM