PARP
|
|
PARP 속성
- 저장 조건
- −70°C
- 물리적 상태
- 완충된 글리세롤 수용액
안전
| 위험품 표기 | B,T,N,Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 20/22-24-37/38-41-51/53-43-36-20/21/22 | ||
| 안전지침서 | 23-24/25-45-36/37/39-26-61-36/37 | ||
| WGK 독일 | 1 |
PARP C화학적 특성, 용도, 생산
용도
PARP-1 is a nuclear enzyme that synthesizes ADP-ribose polymers from NAD+, specifically binds Zn2+ and DNA, and recognizes single-strand breaks in DNA. PARP1 has been used in a study to assess racial and tissue-specific cancer risk associated with polymorphism in the PARP1 gene. It has also been used in a study to investigate inhibitors of PARP-1 for potential cancer treatments.일반 설명
Poly(ADP-ribose) polymerase 1 (PARP-1) is associated with the inflammation response during atherosclerosis.Biochem/physiol Actions
PARP-1 is inactivated by cleavage into a 24kDA and 89kDA fragment by activated caspase-3 or caspase-7. This results in the decreased ability to repair DNA damage and an increase in apoptosis.PARP 준비 용품 및 원자재
원자재
준비 용품
PARP 공급 업체
글로벌( 26)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
| Guangzhou Tomums Life Science Co., Ltd. | 020-31155029 18902330969 |
sales@tomums.cn | China | 4698 | 58 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 15926423062 |
422450190@qq.com | China | 10132 | 58 |
| Shanghai Huzhen Industrial Co., LTD | 021-60345367 13916550749 |
sales@shzbio.com | China | 9965 | 58 |
| United States Biological | -- |
sales@advtechind.com | United States | 6106 | 58 |