CGP 35348

CGP 35348 구조식 이미지
카스 번호:
123690-79-9
상품명:
CGP 35348
동의어(영문):
CGP 35348;CGP 35348 hydrate;(3-AMINOPROPYL)(DIETHOXYMETHYL)PHOSPHINIC ACID;Phosphinic acid, (3-aminopropyl)(diethoxymethyl)-;P-(3-Aminopropyl)-P-(diethoxymethyl)phosphinic acid;Phosphinic acid, P-(3-aminopropyl)-P-(diethoxymethyl)-;(3-Aminopropyl)(diethoxymethyl)phosphinic acid hydrate;spatial learning,neuromuscular,neonatal damage,CGP-35348,brain penetrant,GABA Receptor,CGP35348,Gamma-aminobutyric acid Receptor,centrally,GABAB,CGP 35348,Inhibitor,γ-Aminobutyric acid Receptor,inhibit,active
CBNumber:
CB4386728
분자식:
C8H20NO4P
포뮬러 무게:
225.22
MOL 파일:
123690-79-9.mol
MSDS 파일:
SDS

CGP 35348 속성

저장 조건
−20°C
용해도
H2O: >10 mg/mL
물리적 상태
고체
물리적 상태
단단한 모양
색상
하얀색
수용성
Soluble in water (100mM)

안전

WGK 독일 3

CGP 35348 C화학적 특성, 용도, 생산

용도

CGP 35348 hydrate has been used as a γ-aminobutyric acid-B (GABAB) receptor inhibitor:
  • to study its effects on intrinsic optical signal (IOS) in rat hippocampus
  • alone or in combination with sodium salicylate to study its effects on auditory responses in the rat′s dorsal cortex of rat
  • to study its effects on hepatocellular carcinoma cells (HCC)

생물학적 활성

Selective, brain penetrant GABA B receptor antagonist (IC 50 = 34 μ M as measured in rat cortical membranes). Has higher affinity for postsynaptic versus presynaptic receptors.

Biochem/physiol Actions

CGP 35348 is a γ-aminobutyric acid-B (GABAB) receptor antagonist. It has a higher affinity towards post-versus presynaptic receptors that can penetrate the blood-brain barrier.

CGP 35348 준비 용품 및 원자재

원자재

준비 용품


CGP 35348 공급 업체

글로벌( 38)공급 업체
공급자 전화 이메일 국가 제품 수 이점
TargetMol Chemicals Inc.
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Aladdin Scientific
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3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
3bsc@sina.com China 15848 69
Ascent Scientific 4401179829988
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Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80
EMMX Biotechnology LLC 888-539-0666
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Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720
klq@cw-bio.com China 3444 55
BOC Sciences --
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ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11289 58
Energy Chemical 021-58432009 400-005-6266
marketing1@energy-chemical.com China 44894 58

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