3-Nitroacetophenone
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3-Nitroacetophenone 속성
- 녹는점
- 76-78 °C(lit.)
- 끓는 점
- 202 °C(lit.)
- 밀도
- 1.3450 (rough estimate)
- 증기압
- 0.32Pa at 25℃
- 굴절률
- 1.5468 (estimate)
- 인화점
- 202°C
- 저장 조건
- Sealed in dry,Room Temperature
- 용해도
- DMSO(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 결정성 분말
- 색상
- 노란색에서 노란색-녹색
- 냄새
- 냄새 없는
- 수용성
- 20°C에서 <0.01g/100mL
- BRN
- 743002
- 안정성
- 안정적인. 강한 산화제, 강한 염기와 호환되지 않습니다.
- InChIKey
- ARKIFHPFTHVKDT-UHFFFAOYSA-N
- LogP
- 1.42
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 21 | ||
| 안전지침서 | 22-24/25 | ||
| WGK 독일 | 2 | ||
| RTECS 번호 | AM9625000 | ||
| TSCA | Yes | ||
| HS 번호 | 29147090 | ||
| 유해 물질 데이터 | 121-89-1(Hazardous Substances Data) | ||
| 독성 | mouse,LD50,intraperitoneal,200mg/kg (200mg/kg),National Technical Information Service. Vol. AD277-689, |
3-Nitroacetophenone C화학적 특성, 용도, 생산
화학적 성질
white to light beige crystalline powder or yellow needle-like crystals. soluble in hot water and ether, slightly soluble in ethanol. can be volatile with water vapor.용도
3''-Nitroacetophenone is used as a reactant in the synthesis of fluorine based aminothiazoles with antimicrobial activity.제조 방법
3-Nitroacetophenone is synthesized from acetophenone by nitration.Synthesis of 3-nitroacetophenone
생산 방법
Acetophenone is carefully dissolved in concentrated sulfuric acid at 0 ℃, and mixed acid is added slowly below 0 ℃. The crude product is precipitated by quenching into ice, filtered, and washed acid free. Purification, mainly from the ortho isomer, is achieved by recrystallization from ethanol with significant lowering of the overall yield to ca. 55 %.일반 설명
3-nitroacetophenone is a light beige powder. It is an anthropogenic compound which is used as a synthetic intermediate in the production of dyes and other organic compounds. (NTP, 1992)공기와 물의 반응
Insoluble in water.반응 프로필
A nitrated ketone. Ketones are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.화재위험
Flash point data for 3-Nitroacetophenone are not available, however 3-Nitroacetophenone is probably combustible.Purification Methods
Distil the ketone in steam and crystallise it from EtOH. [Beilstein 7 IV 656.]3-Nitroacetophenone 준비 용품 및 원자재
원자재
준비 용품
ETHYL 5-(3-NITROPHENYL)-1H-PYRAZOLE-3-CARBOXYLATE
3-ACETYLBENZONITRILE
APLPHA-BROMO-M-BENZOYLOXYACETOPHENONE
3-NITROPHENYLACETYLENE
5-(3-NITRO-PHENYL)-1H-PYRAZOLE-3-CARBOXYLIC ACID
(2E)-1-(3-nitrophenyl)-3-(2,3,4-trimethoxyphenyl)prop-2-en-1-one
ETHYL 4-(3-NITROPHENYL)-2,4-DIOXOBUTANOATE
3-Aminoacetophenone
1-Propanone, 3-(dimethylamino)-1-(3-nitrophenyl)-
(2E)-1-(3-nitrophenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one
3-Nitroacetophenone 공급 업체
글로벌( 480)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5993 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 7377 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 |
sales02@airuikechemical.com | China | 994 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 |
sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21695 | 55 |
| Tianjin Zhongxin Chemtech Co., Ltd. | +86-022-66880623 +8618622897568 |
sales@tjzxchem.com | China | 559 | 58 |
| Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 |
kaia@neputrading.com | China | 1011 | 58 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |