3-CHLORO-5-(TRIFLUOROMETHYL)BENZOIC ACID

3-CHLORO-5-(TRIFLUOROMETHYL)BENZOIC ACID 구조식 이미지
카스 번호:
53985-49-2
상품명:
3-CHLORO-5-(TRIFLUOROMETHYL)BENZOIC ACID
동의어(영문):
3-Chloro-5-carboxybenzotrifluoride;3-CHLORO-5-(TRIFLUOROMETHYL)BENZOIC ACID;Benzoic acid, 3-chloro-5-(trifluoromethyl)-;3-Carboxy-5-chlorobenzotrifluoride, 5-Chloro-alpha,alpha,alpha-trifluoro-m-toluic acid
CBNumber:
CB4435008
분자식:
C8H4ClF3O2
포뮬러 무게:
224.56
MOL 파일:
53985-49-2.mol

3-CHLORO-5-(TRIFLUOROMETHYL)BENZOIC ACID 속성

녹는점
98-101℃
끓는 점
263℃
밀도
1.523
인화점
113℃
저장 조건
Sealed in dry,Room Temperature
수용성
물에 용해됩니다.
CAS 데이터베이스
53985-49-2
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
HS 번호 2916399090
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고 GHS hazard pictograms
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P304+P340 흡입하면 신선한 공기가 있는 곳으로 옮기고 호흡하기 쉬운 자세로 안정을 취하시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
P405 밀봉하여 저장하시오.
NFPA 704
0
2 0

3-CHLORO-5-(TRIFLUOROMETHYL)BENZOIC ACID C화학적 특성, 용도, 생산

용도

2-Chloro-5-(trifluoromethyl)benzoic acid may be used as surrogate standard to investigate the exposure and home contamination in urine and hand wipe samples collected from farmers.

Synthesis

1.png
A solution of tBuONO (35.2 g) and CuCl (38.6 g) in CH3CN (375 mL) was warmed to 45-50° C. The compound (50.0 g) obtained in step 2 was added slowly while cooling the reaction mixture to maintain 45-50° C. After stirring at 50° C. for 30 min, the mixture was cooled to 10° C. 6N Hydrochloric acid (250 mL) was added and the mixture was stirred for 10 min. The resultant product was extracted twice with ethyl acetate. The organic layer was-washed with 10% aqueous citric acid solution and water and dried, and the solvent was evaporated under reduced pressure. The obtained residue was purified by silica gel column chromatography (solvent gradient; 10→25% ethyl acetate/hexane) to give 3-chloro-5-(trifluoromethyl)benzoic acid (33.1 g, 60%) as a white powder.

3-CHLORO-5-(TRIFLUOROMETHYL)BENZOIC ACID 준비 용품 및 원자재

원자재

준비 용품


3-CHLORO-5-(TRIFLUOROMETHYL)BENZOIC ACID 공급 업체

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