5'-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE

5'-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE 구조식 이미지
카스 번호:
979-92-0
상품명:
5'-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE
동의어(영문):
S-ADENOSYL-L-HOMOCYSTEINE;s-adenosylhomocysteine;ADOHCY;hpce;Adenosylhomocysteine;S-Adenosyl-L-homocystein;S-(5'-ADENOSYL)-L-HOMOCYSTEINE;5'-DEOXY-S-ADENOSYL-;Adenosyl-L-homocysteine;L-S-AdenosylhoMocysteine
CBNumber:
CB4451354
분자식:
C14H20N6O5S
포뮬러 무게:
384.41
MOL 파일:
979-92-0.mol
MSDS 파일:
SDS

5'-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE 속성

녹는점
209-211 °C
끓는 점
787.5±70.0 °C(Predicted)
밀도
1.91±0.1 g/cm3(Predicted)
저장 조건
-20°C
용해도
1 M HCl: 용해성19.60 - 20.40mg/mL, 투명하거나 약간 흐릿함, 무색 내지 희미한 노란색
물리적 상태
수정 같은
산도 계수 (pKa)
2.22±0.10(Predicted)
색상
황백색에서 갈색까지
BRN
99188
안정성
흡습성
InChIKey
ZJUKTBDSGOFHSH-WFMPWKQPSA-N

안전

WGK 독일 3
F 고인화성물질 8-10-23
HS 번호 2934990002

5'-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE C화학적 특성, 용도, 생산

개요

S-Adenosyl-L-homocysteine (SAH) is an amino acid derivative and an intermediate, by-product, or modulator of several metabolic pathways, including the activated methyl cycle and cysteine biosynthesis. It is also a product of S-adenosyl-methionine (SAM)-dependent methylation of biological molecules, including DNA, RNA, and histones and other proteins. SAH is a risk factor for many diseases, including cancer and neurodegenerative diseases. In addition, inhibitors that block its hydrolysis are being developed as anti-viral, anti-parasitic, anti-arthritic and immunosuppressive agents.

화학적 성질

Pale Beige Solid

용도

A novel biomarker for predicting susceptibility of a subject to a mental or neurodegenerative disorder.

정의

ChEBI: The S-adenosyl derivative of L-homocysteine.

Purification Methods

It has been recrystallised several times from aqueous EtOH or H2O to give small prisms and has max 260nm in H2O. The picrate has m 170o(dec) from H2O. [Baddiley & Jameison J Chem Soc 1085 1955, de la Haba & Cantoni J Biol Chem 234 603 1959, Borchardt et al. J Org Chem 41 565 1976, NMR: Follmann et al. Eur J Biochem 47 187 1974, Beilstein 26 III/IV 3676.]

5'-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE 준비 용품 및 원자재

원자재

준비 용품


5'-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE 공급 업체

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