N6-CYCLOHEXYLADENOSINE
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N6-CYCLOHEXYLADENOSINE 속성
- 녹는점
- 182 - 184°C
- 끓는 점
- 675.2±65.0 °C(Predicted)
- 밀도
- 1.71±0.1 g/cm3(Predicted)
- 저장 조건
- 2-8°C
- 용해도
- DMSO(약간 용해됨), 에탄올(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 13.12±0.70(Predicted)
- 색상
- 흰색에서 황백색까지
- 안정성
- 흡습성
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
WGK 독일 | 3 | ||
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HS 번호 | 29349990 |
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신호 어: | Warning | ||||||||||||||||||||||||||||||||||||||||||
유해·위험 문구: |
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예방조치문구: |
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N6-CYCLOHEXYLADENOSINE C화학적 특성, 용도, 생산
개요
N6-Cyclohexyladenosine is an adenosine receptor agonist. It selectively binds to adenosine A1 receptors in rat cortical membranes (IC50 = 2.3 nM) over A2 receptors in rat striatal membranes (IC50 = 870 nM). N6-Cyclohexyladenosine decreases heart rate and increases coronary flow in a perfused working rat heart model ex vivo (EC25s = 5 and 860 nM, respectively). In vivo, it decreases heart rate and blood pressure in normotensive rats (EC25s = 2.4 and 4.2 μg/kg, respectively). N6-Cyclohexyladenosine (100 μM) induces sleep in rats when administered via basal forebrain infusion. N6-Cyclohexyladenosine also decreases locomotor activity in mice (ED50 = 60 μg/kg, i.p.).용도
N6-Cyclohexyladenosine is a derivative of Adenosine (A280400), and is used testing adenosine A1 and A2A receptor activation for pharmaceuticals such as antidepressants. N6-Cyclohexyladenosine also is used as a JAK2 inhibitor, blocking STAT3 signalling in human cancer cells.Biochem/physiol Actions
Selective A1 adenosine receptor agonist.N6-CYCLOHEXYLADENOSINE 준비 용품 및 원자재
원자재
N-cyclohexyl-7H-purin-6-amine
Adenosine, 2-chloro-N-cyclohexyl-
6-Chloropurine ribonucleoside
9-[2,3,5-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL]-2,6-DICHLOROPURINE
하이포크산틴
시클로헥실아민
이노신
준비 용품
N6-CYCLOHEXYLADENOSINE 공급 업체
글로벌( 55)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
Nanjing Baifuli Technology Co., Ltd. | +86-15335185688 |
sales@unisyn.cn | CHINA | 332 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
NewCan Biotech Limited | +86-0571-86912261 +8613735419629 |
sales@newcanbio.com | China | 10027 | 58 |
Aladdin Scientific | +1-833-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
Amadis Chemical Company Limited | 571-89925085 |
sales@amadischem.com | China | 131981 | 58 |
Nanjing Chemlin Chemical Co., Ltd | 025-83697070 |
info@chemlin.com.cn | China | 17938 | 64 |
Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 |
info@sagechem.com | China | 10269 | 58 |
Chengdu NoVi Biotechnology Co., Ltd. | 028-81458053 |
novibiotech@163.com sales@novi-biotech.com | China | 226 | 55 |
Haoyuan Chemexpress Co., Ltd. | 021-58950125 |
info@chemexpress.com | China | 7553 | 61 |
N6-CYCLOHEXYLADENOSINE 관련 검색:
Tetramethylthiuram Disulfide
Vulcanization accelerator
2',3'-dideoxy-N(6)-cyclohexyladenosine
ferritin-cyclohexyladenosine
N-ALLYL-N-CYCLOHEXYLADENOSINE
N(6)-allyl-N(6)-cyclohexyladenosine
(2S)-N6-[2-ENDO-NORBORNYL]ADENOSINE
N6-METHYL-2'-DEOXY-ADENOSINE
SDZWAG994
CYCLOHEXYLADENOSINE, N6-[ADENINE-2,8-3H]-,N 6-CYCLOHEXYLADENOSINE-[2,8-3H]
6-(METHYLAMINO)PURINE
6-METHYLAMINOPURINE 9-RIBOFURANOSIDE
6-N-HEXYLAMINOPURINE
N6-CYCLOHEXYLADENOSINE