FPG PROTEIN

FPG PROTEIN 구조식 이미지
카스 번호:
78783-53-6
상품명:
FPG PROTEIN
동의어(영문):
fpg protein from escherichia coli;DNA-formamidopyrimidine glycosylase;Fpg Protein from Escherichia coli, Recombinant;Fpg Protein from Escherichia coli >=90% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution, >20,000 units/mg protein
CBNumber:
CB4498113
분자식:
포뮬러 무게:
0
MOL 파일:
Mol file

FPG PROTEIN 속성

저장 조건
-20°C
물리적 상태
완충된 글리세롤 수용액

안전

위험품 표기 Xi
위험 카페고리 넘버 36/37/38
안전지침서 26-36
WGK 독일 1

FPG PROTEIN C화학적 특성, 용도, 생산

용도

Fpg Protein from Escherichia coli has been used for the assessment of DNA oxidative damage using comet assay.

일반 설명

Fpg contains two domains separated by a flexible hinge.

Biochem/physiol Actions

Fpg is a key enzyme in the DNA base excision repair pathway (BER). It catalyses the excision of a broad spectrum of modified purines. Fpg has both DNA glycosylase activity that removes the mutated base and AP-lyase activity that releases ribose leaving both 5′- and 3′-phosphorylated ends in the DNA. The zinc finger motif at its C-terminus is responsible for the DNA binding and AP-lyase activity. In addition, its N-terminal proline acts as a nucleophile to produce a Schiff base intermediate that is essential for enzyme action.

FPG PROTEIN 준비 용품 및 원자재

원자재

준비 용품


FPG PROTEIN 공급 업체

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Creative Enzymes
1-516-855-7709
info@creative-enzymes.com United States 8748 58
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80
Guangzhou Tomums Life Science Co., Ltd. 020-31155029 18902330969
sales@tomums.cn China 4698 58
Energy Chemical 021-58432009 400-005-6266
marketing@energy-chemical.com China 44941 58

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