Anti-UCP;ANTI-UCP-1;Anti-SLC25A7;Anti-HGNC:12517;ANTI-UCP1 MOUSE (RABBIT);ANTI-UNCOUPLING PROTEIN 1;ANTI-MOUSE UNCOUPLING PROTEIN 1;Anti-UCP1 antibody produced in goat;ANTI-UNCOUPLING PROTEIN 1 MOUSE (RABBIT);Anti-UCP-1 antibody produced in rabbit
Anti-UCP-1 antibody produced in rabbit has been used in western blotting and immunohistochemistry.
일반 설명
Uncoupling protein (UCP1) is a 32 kDa, mitochondrial inner membrane protein. It is active as a proton channel forming dimer. It can bind purine nucleotides and is capable of being stimulated by fatty acids.
Biochem/physiol Actions
Uncoupling proteins (UCPs) are transporters functioning as enzymatic uncouplers of oxidative phosphorylation. They can return protons pumped by the respiratory chain to the mitochondrial matrix. UCP-1 is exclusively expressed in brown adipose tissue (BAT) in rodents and in neonates where it is regulated by norepinephrine and thyroid hormones. UCP-1 has been shown to depend on CoQ (ubiquinone) as an obligatory co-factor.
