3-베타-하이드록시-5-알파-안드로스텐-17-온
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3-베타-하이드록시-5-알파-안드로스텐-17-온 속성
- 녹는점
- 172-174 °C
- 알파
- 91 º (c=1, CH3OH)
- 끓는 점
- 372.52°C (rough estimate)
- 밀도
- 1.0320 (rough estimate)
- 굴절률
- 1.4709 (estimate)
- 저장 조건
- Refrigerator
- 용해도
- insoluble in H2O; ≥12.35 mg/mL in EtOH; ≥28.27 mg/mL in DMSO
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 15.14±0.60(Predicted)
- 색상
- White to off-white
- 수용성
- 실질적으로 불용성
- Merck
- 3609
- BRN
- 1884007
- InChIKey
- QGXBDMJGAMFCBF-LUJOEAJASA-N
- LogP
- 3.751
- CAS 데이터베이스
- 481-29-8(CAS DataBase Reference)
안전
안전지침서 | 22-24/25 | ||
---|---|---|---|
WGK 독일 | 3 | ||
F 고인화성물질 | 21 | ||
HS 번호 | 29144000 |
3-베타-하이드록시-5-알파-안드로스텐-17-온 C화학적 특성, 용도, 생산
개요
Epiandrosterone is a steroid hormone with weak androgenic activity, derived from 5 α-androstane. It is a dehydroepiandrosterone metabolite and an androgen. It is a precursor of testosterone and estradiol with hypolipidemic and anabolic activities.화학적 성질
white to off-white crystalline powder. Musky odor when heated.용도
Epiandrosterone is used for weight loss, to improve athletic performance, to reduce sexual problems, and for many other uses, but there is no good scientific evidence to support its use. Epiandrosterone might also be unsafe.Epiandrosterone is a steroid hormone that is present in normal human urine as a minor constituent , it is a less active 3β-isomer of the androgen Androsterone (A635535). Controlled Substance.
정의
ChEBI: Epiandrosterone is a 3beta-hydroxy steroid that is (5alpha)-androstane substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It has a role as an androgen and a human metabolite. It is a 17-oxo steroid, a 3beta-hydroxy steroid and an androstanoid. It derives from a 5alpha-androstane.Purification Methods
Purify epi-androsterone via the acetate, hydrolyse this and recrystallise it from CHCl3/hexane or aqueous EtOH. The acetate [1239-31-2] is purified by chromatography and when crystallised from pet ether has m 103-104o, []D +68.5o (c 1, CHCl3). The oxime has m 194-196o (from MeOH), []D +17.5o (c 6.2, CHCl3). The racemic ketone is sublimed at 130o/high vacuum and after two crystallisations from methylcyclohexane it gives prisms with m 161-162o (which changed crystal form at 140-145o). [Ruzicka & Wettstein Helv Chim Acta 18 1264 1935, Johnson et al. J Am Chem Soc 75 2275 1953, 78 6331 1956, Cordwell et al. J Chem. Soc 361 1953, Beilstein 8 IV 462.]3-베타-하이드록시-5-알파-안드로스텐-17-온 준비 용품 및 원자재
원자재
Epiandrosterone acetate
5-ALPHA-ANDROSTANE
1,2,4,5-테트라하이드로테스토락톤
에티오콜라논
5a-안드로스탄디온
(8R,9S,10R,13S,14S)-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydrospiro[cyclopenta[a]phenanthrene-17,2-[1,3]dioxolan]-3(2H)-one(WXG00896)
Androsterone
준비 용품
3-베타-하이드록시-5-알파-안드로스텐-17-온 공급 업체
글로벌( 370)공급 업체
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3-베타-하이드록시-5-알파-안드로스텐-17-온 관련 검색:
CHLOROPHOSPHONAZO III
Benzoylformic acid
Methyl cyclopentylphenylglycolate
Androstane-2,17-diol, 3-(4-morpholinyl)-16-(1-pyrrolidinyl)-, (2α,3β,5α,16β,17β)-
Androstan-17-ol, 2,3-epoxy-16-(1-pyrrolidinyl)-, (2β,3β,5α,16β,17β)-
Androstan-17-one,3-[[(4-methylphenyl)sulfonyl]oxy]-,(3,5)-
2a,3a,16a,17a-Diepoxy-17b-acetoxy-5a-androstane
XMUJPIDSOJTMMS-VTBMCCKRSA-N
Androst-3-en-17-one,(5)
pyrrolidinyl)-, (2β,3α,5α,16β,17β)-
ALPHA-PHENYLCYCLOPENTANEACETIC ACID
Androstan-17-one,2,3-epoxy-16-(1-pyrrolidinyl)
7-Keto-dehydroepiandrosterone
Epiandrosterone, 5-dehydro-
Osthole
7-alpha-Hydroxydehydroepiandrosterone
Dehydroepiandrosterone enanthate
5-ALPHA-ANDROSTANE