인산 알루미늄

인산 알루미늄
인산 알루미늄 구조식 이미지
카스 번호:
7784-30-7
한글명:
인산 알루미늄
동의어(한글):
인산알루미늄;알루미늄인산염;알루미늄오르토인산염;인산,알루미늄염;인산알루미늄;인산 알루미늄
상품명:
Aluminium phosphate
동의어(영문):
ALUMINUM PHOSPHATE;Alminum phosphate;Aluminium Phosphite;ALUMINUM ORTHOPHOSPHATE;ffb32;aluphos;phosphalugel;ALUMPHOSPHATE;ALUMINOPHOSPHATE;uminum phosphate
CBNumber:
CB4741378
분자식:
AlO4P
포뮬러 무게:
121.95
MOL 파일:
7784-30-7.mol
MSDS 파일:
SDS

인산 알루미늄 속성

녹는점
1500 °C
밀도
2.56 g/mL at 25 °C (lit.)
저장 조건
Inert atmosphere,Room Temperature
용해도
물에 아주 약간 녹고, 알코올에는 거의 녹지 않습니다. 무기산과 알칼리성 수산화물의 묽은 용액에 용해됩니다.
물리적 상태
가루
Specific Gravity
2.566
색상
하얀색
수용성
불용성
Merck
14,358
Solubility Product Constant (Ksp)
pKsp: 20.01
Dielectric constant
6.0(Ambient)
노출 한도
ACGIH: TWA 1 mg/m3
InChI
InChI=1S/Al.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3
InChIKey
ILRRQNADMUWWFW-UHFFFAOYSA-K
SMILES
[Al+3].P([O-])([O-])([O-])=O
CAS 데이터베이스
7784-30-7(CAS DataBase Reference)
EPA
Monoaluminum phosphate (7784-30-7)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 C
위험 카페고리 넘버 34
안전지침서 26-36/37/39-45
유엔번호(UN No.) UN 3260 8/PG 2
WGK 독일 1
RTECS 번호 TB6450000
TSCA Yes
위험 등급 8
HS 번호 28352990
독성 LD50 oral in mouse: > 5gm/kg
기존화학 물질 KE-01011
그림문자(GHS): GHS hazard pictograms
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H314 피부에 심한 화상과 눈에 손상을 일으킴 피부부식성 또는 자극성물질 구분 1A, B, C 위험 GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H318 눈에 심한 손상을 일으킴 심한 눈 손상 또는 자극성 물질 구분 1 위험 GHS hazard pictograms P280, P305+P351+P338, P310
예방조치문구:
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P301+P330+P331 삼켰다면 입을 씻어내시오. 토하게 하려 하지 마시오.
P303+P361+P353 피부(또는 머리카락)에 묻으면 오염된 모든 의복은 벗거나 제거하시오 피부를 물로 씻으시오/샤워하시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
P310 즉시 의료기관(의사)의 진찰을 받으시오. 삼켰다면 즉시 의료기관(의사)의 도움을 받으시오.
P405 밀봉하여 저장하시오.
NFPA 704
1
2 0

인산 알루미늄 C화학적 특성, 용도, 생산

개요

Aluminium phosphate occurs in nature as the mineral, berlinite. Also, it occurs in nature in minerals, amblygonite, [NaAl(PO4)(OH)]; augelite, [Al2(PO4)(OH)3]; lazulite, [(Mg,Fe)Al2(PO4)2(OH)2]; variscite [(Al,Fe3+)(PO4)•2H2O]; and wavellite, [Al3(OH)3•(PO4)2•5H2O]. It is used as flux for ceramics; as cement in combination with calcium sulfate and sodium silicate; and in the manufacture of special glasses. It is also used in dried gel and therapeutically as an antacid.

물리적 성질

White powdery solid (rhombic plate); the mineral berlinite (AlPO4) has hexagonal quartz-like structure; refractive index 1.546; mp > 1,500°C; density 2.566 g/cu3; insoluble in water and alcohol; Ksp 9.83x10-10 very slightly soluble in HCl or HNO3.

출처

The compound occurs in nature as the mineral, berlinite. Also, it occurs in nature in minerals, amblygonite, [NaAl(PO4)(OH)]; augelite, [Al2(PO4)(OH)3]; lazulite, [(Mg,Fe)Al2(PO4)2(OH)2]; variscite [(Al,Fe3+)(PO4)?2H2O]; and wavellite, [Al3(OH)3?(PO4)2?5H2O]. It is used as flux for ceramics; as cement in combination with calcium sulfate and sodium silicate; and in the manufacture of special glasses. It is also used in dried gel and therapeutically as an antacid.

용도

Antacid; vaccine adjuvant

제조 방법

It is prepared by treating sodium aluminate with phosphoric acid.

생산 방법

Aluminum phosphate adjuvant is formed by the reaction of a solution of aluminum chloride and phosphoric acid with alkali hydroxide.

일반 설명

A colorless liquid. Insoluble in water. Corrosive to metals and tissue.

공기와 물의 반응

Insoluble in water.

반응 프로필

An acid. The resulting aqueous solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions.

위험도

Solutions are corrosive to tissue.

건강위험

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

화재위험

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.

Pharmaceutical Applications

Aluminum phosphate adjuvant is used in parenteral human and veterinary vaccines.It activates Th2 immune responses, including IgG and IgE antibody responses.

Clinical Use

Phalu Gel's main active ingredient is aluminum Phosphorus. Aluminum Phosphate works to reduce excess stomach acid. This gel suspension, when taken to the stomach, will form a protective layer on the surface of the gastrointestinal mucosa, similar to the effect of mucus or mucosal protective factors to help cover the stomach from the impact of fluids. The aluminum phosphate layer in the stomach has a smooth dispersion effect, going to the ulcers in the stomach and making them heal faster, making the patient feel more comfortable and less painful. Aluminum Phosphorus, when used, does not affect the intestinal absorption of Phosphorus. Phalu-Gel will quickly reduce the pain of stomach ulcers and the discomfort of excess acid, help heal the ulcers quickly, and make the patient feel comfortable right away.Aluminum hydroxide, aluminum phosphate, and potassium aluminum sulfate (alum) are used as adjuvants in vaccines designed to stimulate systemic immunity. Aluminum salts are used in DPT, pneumocccal conjugate, hepatitis A, papilloma, anthrax, and rabies vaccines. Like other systemic adjuvants, they form an insoluble depot and slowly release the antigen, which stimulates an antibody response.

Safety Profile

Corrosive to the eyes, skin, and mucous membranes. When heated to decomposition it emits toxic fumes of POx. Used as an antacid and as a cement component, flux for ceramics, dental cement, glass, and gels. See also ALUMINUM COMPOUNDS and PHOSPHATES

Safety

Aluminum phosphate adjuvant is intended for use in parenteral vaccines and is generally regarded as safe. It may cause mild irritation, dryness, and dermatitis on skin contact. It may also cause redness, conjunctivitis, and short-term mild irritation on eye contact. Ingestion of large amounts of aluminum phosphate adjuvant may cause respiratory irritation with nausea, vomiting, and constipation. Inhalation is unlikely, although the dried product may cause respiratory irritation and cough. Type I hypersensitivity reactions following parenteral administration have also been reported.

잠재적 노출

Used as a flux in ceramics; in dental cements; in the manufacture of special glasses, paints and varnishes, cosmetics; making pulp and paper; as an antacid.

저장

Aluminum phosphate adjuvant is stable for at least 2 years when stored at 4–308℃ in well-sealed inert containers. It must not be allowed to freeze as the hydrated colloid structure will be irreversibly damaged.

운송 방법

UN1760 Corrosive liquids, n.o.s., Hazard class: 8; Labels: 8-Corrosive material, Technical Name Required. UN3260 Corrosive solid, acidic, inorganic, n.o.s., Hazard class: 8; Labels: 8-Corrosive material, Technical Name Required.

비 호환성

A strong oxidizer; keep away from combustible materials. Violent reaction with reducing agents; strong bases. Material is an inorganic acid and will react, possibly violently, with bases; corrosive to metals, some plastics and body tissues

Regulatory Status

GRAS listed. Accepted for use in human and veterinary vaccines in Europe and the USA. The limits for use in human vaccines are 0.85 mg aluminum/dose (FDA) and 1.25 mg aluminum/dose (WHO). There are no established limits for use in veterinary vaccines. Reported in the EPA TSCA Inventory.

인산 알루미늄 준비 용품 및 원자재

원자재

준비 용품


인산 알루미늄 공급 업체

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