3-chloro-4-(pyridin-2-ylmethoxy)aniline
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3-chloro-4-(pyridin-2-ylmethoxy)aniline 속성
- 녹는점
- 91.0 to 95.0 °C
- 끓는 점
- 402.5±35.0 °C(Predicted)
- 밀도
- 1.292±0.06 g/cm3(Predicted)
- 저장 조건
- Keep in dark place,Inert atmosphere,Room temperature
- 물리적 상태
- powder to crystal
- 산도 계수 (pKa)
- 3.88±0.10(Predicted)
- 색상
- White to Light yellow to Light orange
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| HS 번호 | 2933399990 |
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3-chloro-4-(pyridin-2-ylmethoxy)aniline C화학적 특성, 용도, 생산
용도
3-Chloro-4-(2-pyridylmethoxy)aniline was used for preparation of disubstituted (arylamino)quinolinecarbonitriles as orally active irreversible inhibitors of human epidermal growth factor receptor-2 kinase activity and antitumor agents.Synthesis
3-chloro-4-(pyridin-2-ylmethoxy)aniline is synthesised using 2-((2-Chloro-4-nitrophenoxy)methyl)pyridine as a raw material by chemical reaction. The specific synthesis steps are as follows:The 2-((2-chloro-4-nitrophenoxy)methyl)pyridine (3.9 g, 15 mmol), zinc powder (5.8 g, 88 mmol) and ammonium chloride (2.4 g, 44 mmol) were added into a mixed solution of ethanol (60 mL) and H2O (10 mL). The mixture was stirred at 60° C. overnight. Then the reaction mixture was poured into 200 mL of H2O, extracted with ethyl acetate. The organic phase was separated, washed with saturated brine and dried. The solvent was removed in vacuo, and the compound shown in the title (3.4 g, 98percent) was obtained. 1H NMR (CDCl3): δ 8.57 (1H, d, J=4.8 Hz), 7.75-7.70 (1H, m), 7.65-7.63 (1H, m), 7.23-7.20 (1H, m), 6.81 (1H, d, J=9.2 Hz), 6.77 (1H, d, J=2.8 Hz), 5.18 (2H, s), 3.48 (2H, br).
3-chloro-4-(pyridin-2-ylmethoxy)aniline 준비 용품 및 원자재
원자재
준비 용품
3-chloro-4-(pyridin-2-ylmethoxy)aniline 공급 업체
글로벌( 253)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Shanghai Yingrui Biopharma Co.,Ltd | 21-33585366 |
export01@shyrchem.com | CHINA | 1320 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 |
sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21695 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9352 | 55 |
| Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ |
sales03@shyrchem.com | CHINA | 738 | 60 |
| Anqing Chico Pharmaceutical Co., Ltd. | 15380796838 |
chloewu@chicopharm.cn | CHINA | 341 | 58 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | 18957127338 |
stella@zetchem.com | China | 2141 | 58 |
| Hangzhou Cyanochem Co., Ltd. | +86 17788583750 |
sales@cyanochem.com | CHINA | 283 | 58 |
3-chloro-4-(pyridin-2-ylmethoxy)aniline 관련 검색:
n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide
6-amino-4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-7-ethoxyquinoline-3-carbonitrile
2-[(2-Chloro-4-nitrophenoxy)methyl]pyridine
Neratinib
2-(CHLOROMETHYL)ALLYLTRICHLOROSILANE
3-Bromofuran
6-AMino-4-((3-chloro-4-(pyridin-2-ylMethoxy)phenyl)aMino)-7-ethoxyquinoline-3-carbonitrile (Hydrochloride)
2-(4-Nitro-2-ethoxyphenyl)pthaliMide
N-(3-cyano-7-ethoxy-4-oxo-1,4-dihydroquinolin-6-yl)acetamide
2-(4-AMino-2-ethoxyphenyl)pthaliMide
6-AMINO-4-CHLORO-7-ETHOXYQUINOLINE-3-CARBONITRILE
6-fluoroquinoline-3-carbonitrile
3-METHOXYPYRIDINE
4-Chloro-3-cyano-7-ethoxy-6-nitroquinoline
2-Amino-5-chloropyridine-3-carboxylic acid
4-(4-amino-2-fluorophenoxy)-3-chloro-N-(diphenylmethylene)-2-Pyridinamine
3-chloro-4-(pyridin-2-ylmethoxy)aniline
3-chloro-4-(pyridin-2-ylmethoxy)aniline