페니실린 G 칼륨

페니실린 G 칼륨
페니실린 G 칼륨 구조식 이미지
카스 번호:
113-98-4
한글명:
페니실린 G 칼륨
동의어(한글):
페니실린G칼륨;페니실린G칼륨
상품명:
Penicillin G potassium salt
동의어(영문):
PENICILLIN G POTASSIUM;BENZYLPENICILLIN POTASSIUM;PENICILLIN G POTASSIUM SALT;PENICILLIN G POTASSIUM SALT;pfizerpen;Penicilline G;potassium [2s-(2alpha,5alpha,6beta)]-3,3-dimethyl-7-oxo-6-(phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;Pen-G;forpen;PENICILLINE G POTASSIUM
CBNumber:
CB4855484
분자식:
C16H17KN2O4S
포뮬러 무게:
372.48
MOL 파일:
113-98-4.mol
MSDS 파일:
SDS

페니실린 G 칼륨 속성

녹는점
214-217 C
알파
D22 +285° (c = 0.748 in water)
굴절률
294 ° (C=1, H2O)
저장 조건
Sealed in dry,Store in freezer, under -20°C
용해도
H2O: 100 mg/mL
물리적 상태
가루
색상
부탄올(수용액)에서 결정화된 바늘
수소이온지수(pH)
pH (10g/L, 25℃) : 5.0~7.5
수용성
물(100 mg/ml), 메탄올, 에탄올(드물게) 및 알코올에 용해됩니다. 클로로포름에 불용성.
Merck
14,7094
BRN
3832841
안정성
흡습성
InChIKey
IYNDLOXRXUOGIU-LQDWTQKMSA-M
EPA
Penicillin G Potassium (113-98-4)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xn,C,F
위험 카페고리 넘버 42/43-34-11
안전지침서 36/37-45-36/37/39-26-16-60-37-24-22
WGK 독일 2
RTECS 번호 XH9700000
F 고인화성물질 10-23
TSCA Yes
HS 번호 29411000
독성 LD50 oral in rabbit: 5848mg/kg
기존화학 물질 KE-11721
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H317 알레르기성 피부 반응을 일으킬 수 있음 피부 과민성 물질 구분 1 경고 GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P272 작업장 밖으로 오염된 의복을 반출하지 마시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P302+P352 피부에 묻으면 다량의 물로 씻으시오.
P333+P313 피부자극성 또는 홍반이 나타나면 의학적인 조치·조언를 구하시오.
NFPA 704
0
2 0

페니실린 G 칼륨 MSDS


potassium [2S-(2alpha,5alpha,6beta)]-3,3-dimethyl-7-oxo-6-(phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

페니실린 G 칼륨 C화학적 특성, 용도, 생산

화학적 성질

Penicillin G potassium salt is also known as Potassium benzylpenicillin, it is white crystalline powder, odorless or slightly specific odor, hygroscopic. Soluble in water, physiological saline, glucose solution. The aqueous solution of it is easy to fail when placed at room temperature, and it will fail rapidly in the presence of acid, alkali, oxidant, etc. Penicillin G potassium salt has good antibacterial effect on Streptococcus such as Streptococcus hemolyticus, Streptococcus pneumoniae and Staphylococcus without penicillinase.

용도

Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. Penicillin G potassium salt is used as a cell culture additive as an antibiotics. Use to inhibit the synthesis of bacterial cell walls by inhibition of the cell wall peptidoglycan chain cross-lining. It is the drug of choice for groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridians group streptococci, and non-penicillinase producing staphylococcus. The potassium salt has been used to study murosomes of staphylococci and the penicillin-induced lysis of Streptococcus mutans.

정의

ChEBI: Penicillin G potassium salt is organic potassium salt of benzylpenicillin. It is an antibiotic substance produced by Penicillium sp. Antibacterial. It contains a benzylpenicillin(1-).

제조 방법

Penicillin G potassium salt is a highly effective and low toxicity antibiotic, which is obtained by salt formation of Chlorpheniramine maleate and maleic acid.

일반 설명

Penicillin G Potassium is the potassium salt form of penicillin G, a broad-spectrum penicillin antibiotic. Penicillin G potassium binds to penicillin binding proteins (PBP), the enzymes that catalyze the synthesis of peptidoglycan, which is a critical component of the bacterial cell wall. This leads to the interruption of cell wall synthesis, consequently leading to bacterial cell growth inhibition and cell lysis.

Biochem/physiol Actions

Mode of Action: Penicillin G acts by inhibiting cell wall synthesis through binding to penicillin binding proteins (PBPs), inhibiting peptidoglycan chain cross-linking.
Antimicrobial spectrum: This product is active against gram-positive and gram-negative bacteria.

Safety Profile

Poison by intracerebral andintravenous routes. Moderately toxic by intraperitonealroute. Mutation data reported. See other penicillin entries.When heated to decomposition it emits toxic fumes ofNOx and SOx.

페니실린 G 칼륨 준비 용품 및 원자재

원자재

준비 용품


페니실린 G 칼륨 공급 업체

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