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피리트라마이드

피리트라마이드
피리트라마이드 구조식 이미지
카스 번호:
302-41-0
한글명:
피리트라마이드
동의어(한글):
피리트라마이드
상품명:
piritramide
동의어(영문):
A 65;R 3365;Pirdolan;Piridolan;Dipidolor;Pirtramide;piritramide;Pirinitramide;DipiritraMide;Piritramide (1 mg/mL in Methanol)
CBNumber:
CB4893624
분자식:
C27H34N4O
포뮬러 무게:
430.59
MOL 파일:
302-41-0.mol

피리트라마이드 속성

녹는점
149-150°
끓는 점
544.82°C (rough estimate)
밀도
1.0967 (rough estimate)
굴절률
1.5900 (estimate)
저장 조건
Controlled Substance, -20°C Freezer
산도 계수 (pKa)
16.19±0.20(Predicted)

안전

피리트라마이드 C화학적 특성, 용도, 생산

화학적 성질

Off-White Low Melting Solid

Originator

Dipidolor ,Janssen W. ,Germany,1969

용도

Piritramide is a synthetic opioid commonly used in Germany and Austria for the analgesia of pediatric patients.

Manufacturing Process

A mixture of 84 parts of 3,3-diphenyl-3-cyanopropyl bromide, 41 parts of 4piperidino-4-piperidinecarboxamide, 64 parts of sodium carbonate, a small amount of potassium iodide and 1,200 parts of anhydrous toluene was stirred, and heated under reflux for 48 hours. At the end of this time the reaction mixture was allowed to cool to room temperature, and 500 parts of water were added. The resultant precipitate was removed by filtration, and triturated with diisopropyl ether. The crystalline material thus obtained was removed by filtration, and recrystallized from 320 parts of acetone, to give 1-(3,3diphenyl-3-cyanopropyl)-4-piperidino-4-piperidinecarboxamide, melting at about 149°C to 150°C.

Therapeutic Function

Analgesic

피리트라마이드 준비 용품 및 원자재

원자재

준비 용품


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