4-Chloro-1-butanol
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4-Chloro-1-butanol 속성
- 끓는 점
- 84-85 °C/16 mmHg (lit.)
- 밀도
- 1.088 g/mL at 25 °C (lit.)
- 굴절률
- n
20/D 1.453(lit.)
- 인화점
- 97 °F
- 저장 조건
- 2-8°C
- 용해도
- 메탄올, 클로로포름 및 디메틸 설폭사이드에 용해됩니다.
- 물리적 상태
- 액체
- 산도 계수 (pKa)
- 15.01±0.10(Predicted)
- 색상
- 무색투명~연황색
- BRN
- 1731408
- InChIKey
- HXHGULXINZUGJX-UHFFFAOYSA-N
- CAS 데이터베이스
- 928-51-8(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn,C,F | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 10-22-36/37/38-20/21/22-34-40 | ||
| 안전지침서 | 23-24/25-36/37/39-26-16-36/37 | ||
| 유엔번호(UN No.) | UN 2920 8/PG 2 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | EL1325000 | ||
| 위험 참고 사항 | Harmful | ||
| TSCA | Yes | ||
| 위험 등급 | 3.2 | ||
| 포장분류 | III | ||
| HS 번호 | 29055910 |
4-Chloro-1-butanol C화학적 특성, 용도, 생산
화학적 성질
CLEAR COLOURLESS LIQUID용도
4-Chloro-1-butanol is employed as an internal standard in the analysis of genotoxic impurities in active pharmaceutical ingredients by GC-MS technique.정의
ChEBI: A primary alcohol that is butan-1-ol substituted by a chloro group at position 4.일반 설명
4-Chloro-1-butanol, an alkylating agent, is one of the genotoxic impurity in active pharmaceutical ingredients. Reaction of 4-chloro-1-butanol and Reichardt′s dye has been monitored spectrophotometrically for the determination of genotoxic impurities in pharmaceuticals.건강위험
The toxicity of this compound is low. How ever, the acute toxic symptoms are those ofethylene and propylene chlorohydrins. Oralintake of this compound caused muscle con traction, gastrointestinal pain, ulceration, andliver injury in test animals.LD50 value, oral (mice): 990 mg/kg
Tetramethylene chlorohydrin caused tumorsin lungs in test animals. Its carcinogenicity,however, is not yet fully established.
화재위험
Flammable; flash point 36°C (97°F); vapor density 3.7 (air = 1); the vapor forms an explosive mixture with air, range is not reported. Fire-extinguishing agent: “alcohol” foam; a water spray may be used to cool fire-exposed containers and to flush any spill. It decomposes to HCl and tetrahydrofuran on heating.Safety Profile
Moderately toxic by ingestion. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl-. See also CHLORIDES and ALCOHOLS.폐기물 처리
Tetramethylene chlorohydrin is burned ina chemical incinerator equipped with anafterburner and scrubber.4-Chloro-1-butanol 준비 용품 및 원자재
원자재
준비 용품
4-Chloro-1-butanol 공급 업체
글로벌( 379)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12452 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5993 | 58 |
| Hebei Guanlang Biotechnology Co,.LTD | +8619930503252 |
daisy@crovellbio.com | China | 5964 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 |
jack.li@time-chemicals.com | China | 1807 | 55 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 |
admin@nexconn.com | China | 7836 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 |
sales@amoychem.com | China | 6387 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |