A
widely abused drug; a sympathomimetic and central stimulant
that has been used clinically as an anorectic agent. The use of
methamphetamine and related drugs in treating obesity is, however,
now generally discredited. It may cause elevation of
blood pressure, palpitation, and tachycardia, as well as various
CNS effects, including psychotic effects at higher doses.
Chronic use of methamphetamine and related compounds,
especially at high doses as often occurs with drug abuse, can
cause a condition often indistinguishable from schizophrenia.
Abrupt withdrawal may cause fatigue, depression, and sleep
changes. Methamphetamine is an indirect-acting adrenergic
and dopamine agonist that acts principally to release endogenous
catecholamines, thereby increasing their synaptic availability.
Many of its actions can be blocked by adrenergic and
dopamine antagonists. The i.p. LD50 in mice is 70 mg/kg.
장기(또는, 영향을 받은 알려진 모든 장기를 명시)에 손상을 일으킴(노출되어도 특정 표적장기 독성을 일으키지 않는다는 결정적인 노출경로가 있다면 노출경로를 기재)
특정 표적장기 독성 - 1회 노출
구분 1
위험
P260, P264, P270, P307+P311, P321,P405, P501
예방조치문구:
P210
열·스파크·화염·고열로부터 멀리하시오 - 금연 하시오.
P260
분진·흄·가스·미스트·증기·...·스프레이를 흡입하지 마시오.
P280
보호장갑/보호의/보안경/안면보호구를 착용하시오.
P301+P310
삼켰다면 즉시 의료기관(의사)의 진찰을 받으시오.
P311
의료기관(의사)의 진찰을 받으시오.
메탐페타민 C화학적 특성, 용도, 생산
용도
Nasal decongestant.
정의
ChEBI: A member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent.
World Health Organization (WHO)
Metamfetamine, an amfetamine derivative, is controlled under
Schedule II of the 1971 Convention on Psychotropic Substances. See WHO
comment for amfetamine.
(Reference: (UNCPS2) United Nations Convention on Psychotropic Substances (II),
, , 1971)
