Entacapone

Entacapone 구조식 이미지
카스 번호:
116314-67-1
상품명:
Entacapone
동의어(영문):
C071192;Novartis brand of entacapone;N,N-Diethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylamide;2-Cyano-N,N-diethyl-3-(3,4-dihydroxy-5-nitrophenyl)propenamide;2-Propenamide, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-;(E)-2-Cyano-3-(3,4-dihydroxy-5-nitro-phenyl)-N,N-diethyl-prop-2-enamide
CBNumber:
CB51022727
분자식:
포뮬러 무게:
0
MOL 파일:
116314-67-1.mol

Entacapone 속성

안전

Entacapone C화학적 특성, 용도, 생산

Originator

Comtan,Orion Corporation

Manufacturing Process

N,N-Diethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylamide (2- Propenamide, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl).
A solution containing 1.83 g of 3,4-dihydroxy-5-nitrobenzaldehyde, 1.5 g of N,N-diethylcyanoacetamide and catalytic amount of piperidine acetate in 40 ml of dry ethanol was refluxed over night. After cooling the solvent was evaporated in vacuo and the residue was recrystallized from waterdimethylformamide. Yield of desired product was 2.23 g (73%), melting point 153°-156°C.

Therapeutic Function

Antiparkinsonian

Entacapone 준비 용품 및 원자재

원자재

준비 용품


Entacapone 공급 업체

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