ChemicalBook
Chinese English Japanese Germany Korea

트리플루오로아세트 산

트리플루오로아세트 산
트리플루오로아세트 산 구조식 이미지
카스 번호:
76-05-1
한글명:
트리플루오로아세트 산
동의어(한글):
트리플루오로아세트산;퍼플루오로아세트산;퍼플루오로아세트산;트리플루오로에탄산;2,2,2-트리플루오로아세트산;트리플루오로아세트산
상품명:
Trifluoroacetic acid
동의어(영문):
TFA;50ml;25ml;TFA(L);TFA(Kg);CF3COOH;BUFFER A;IPC-PFFA-2;WASH BUFFER;SOXWAVE 3.6
CBNumber:
CB5127175
분자식:
C2HF3O2
포뮬러 무게:
114.02
MOL 파일:
76-05-1.mol

트리플루오로아세트 산 속성

녹는점
-15 °C
끓는 점
72.4 °C(lit.)
밀도
1.535 g/mL at 25 °C(lit.)
증기 밀도
3.9 (vs air)
증기압
97.5 mm Hg ( 20 °C)
굴절률
n20/D 1.3(lit.)
인화점
None
저장 조건
2-8°C
용해도
Miscible with ether, acetone, ethanol, benzene, hexane, and CCl<sub>4</sub>
산도 계수 (pKa)
-0.3(at 25℃)
물리적 상태
Liquid
Specific Gravity
1.480
색상
Colorless
수소이온지수(pH)
1 (10g/l, H2O)
냄새
Sharp, pungent odor
수용성
miscible
감도
Hygroscopic
최대 파장(λmax)
λ: 260 nm Amax: 0.9
λ: 270 nm Amax: 0.10
λ: 280 nm Amax: 0.05
λ: 290 nm Amax: 0.04
λ: 300 nm Amax: 0.03
λ: 320 nm Amax: 0.025
Merck
14,9681
BRN
742035
안정성
Stable. Incompatible with combustible material, strong bases, water, strong oxidizing agents. Non-combustible. Hygroscopic. May react violently with bases.
InChIKey
DTQVDTLACAAQTR-UHFFFAOYSA-N
CAS 데이터베이스
76-05-1(CAS DataBase Reference)
NIST
Acetic acid, trifluoro-(76-05-1)
EPA
Acetic acid, trifluoro-(76-05-1)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 C,T,Xi
위험 카페고리 넘버 20-35-52/53-34
안전지침서 9-26-27-28-45-61-28A-36/37/39
유엔번호(UN No.) UN 2699 8/PG 1
WGK 독일 2
RTECS 번호 AJ9625000
F 고인화성물질 3
위험 참고 사항 Toxic/Corrosive
TSCA T
위험 등급 8
포장분류 I
HS 번호 29159080
유해 물질 데이터 76-05-1(Hazardous Substances Data)
독성 LD50 i.v. in mice: 1200 mg/kg (Airaksinen, Tammisto)
그림문자(GHS):
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H290 금속을 부식시킬 수 있음 금속 부식성물질 구분 1 경고 P234, P390, P404
H314 피부에 심한 화상과 눈에 손상을 일으킴 피부부식성 또는 자극성물질 구분 1A, B, C 위험 P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H332 흡입하면 유해함 급성 독성 물질 흡입 구분 4 경고 P261, P271, P304+P340, P312
H412 장기적 영향에 의해 수생생물에 유해함 수생 환경유해성 물질 - 만성 구분 3 P273, P501
예방조치문구:
P234 원래의 용기에만 보관하시오.
P260 분진·흄·가스·미스트·증기·...·스프레이를 흡입하지 마시오.
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P264 취급 후에는 손을 철저히 씻으시오.
P264 취급 후에는 손을 철저히 씻으시오.
P273 환경으로 배출하지 마시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P310 즉시 의료기관(의사)의 진찰을 받으시오. 삼켰다면 즉시 의료기관(의사)의 도움을 받으시오.
P390 물질손상을 방지하기 위해 누출물을 흡수시키시오.
P301+P330+P331 삼켰다면 입을 씻어내시오. 토하게 하려 하지 마시오.
P303+P361+P353 피부(또는 머리카락)에 묻으면 오염된 모든 의복은 벗거나 제거하시오 피부를 물로 씻으시오/샤워하시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
P405 밀봉하여 저장하시오.
P406 부식을 방지하여 보관하시오/...내부식성 용기
P501 ...에 내용물 / 용기를 폐기 하시오.

트리플루오로아세트 산 MSDS


Trifluoroacetic acid

트리플루오로아세트 산 C화학적 특성, 용도, 생산

화학적 성질

Colorless, fuming liquid; hygroscopic; pungent odor. Very soluble in water. Nonflammable.

용도

Mainly used as an fluorine-containing intermediate in fine chemical, pharmaceutical, pesticide and dye. It is used as a raw material in the process of glass coating , sugar and polypeptide synthetic. It is used as a catalyst in esterification reaction and condensation reaction and a protective agent for hydroxyl and amino.

용도

Suitable for peptide and protein synthesis.

용도

In organic synthesis; dissolves protein when mixed with liquid SO2.

일반 설명

A colorless fuming liquid with a pungent odor. Soluble in water and denser than water. Corrosive to skin, eyes and mucous membranes. Used to make other chemicals and as a solvent.

공기와 물의 반응

Fumes in air. Soluble in water.

반응 프로필

Trifluoroacetic acid is a strong acid; attacks many metals [Handling Chemicals Safely 1980. p. 935]. A 30% solution of hydrogen peroxide in Trifluoroacetic acid is often used to destructively oxidize aromatic rings in preference to the side chains. Explosions have occurred, if the excess peroxide is not catalytically destroyed, prior to removal of solvent, [Tetrahedron Lett., 1977, 1703-1704]. The reduction of amides of Trifluoroacetic acid with lithium aluminum hydride are dangerous at all phases of the process, explosions have occurred, [Chem. Eng. News, 1955, 33, 1368].

건강위험

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

건강위험

Trifluoroacetic acid is a highly corrosive substance. Contact of the liquid with the skin, eyes, and mucous membranes can cause severe burns, and ingestion can result in serious damage to the digestive tract. TFA vapor is highly irritating of the eyes and respiratory tract, and inhalation of high concentrations can lead to severe destruction of the upper respiratory tract and may be fatal as a result of pulmonary edema. Symptoms of overexposure to TFA vapor include a burning feeling, coughing, headache, nausea, and vomiting.
Trifluoroacetic acid has not been found to be carcinogenic or to show reproductive or developmental toxicity in humans.

화재위험

Trifluoroacetic acid is not combustible. Nevertheless, the presence of trifluoroacetic acid at the site of a fire would be of great concern because of its high vapor pressure and extreme corrosiveness.

화재위험

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.

인화성 및 폭발성

Trifluoroacetic acid is not combustible. Nevertheless, the presence of trifluoroacetic acid at the site of a fire would be of great concern because of its high vapor pressure and extreme corrosiveness.

Safety Profile

Poison by ingestion and intraperitoneal routes. Moderately toxic by intravenous route. Mildly toxic by inhalation. A corrosive irritant to skin, eyes, and mucous membranes. When heated to decomposition it emits toxic fumes of F-. Used as a strong organic acid catalyst.

저장

trifluoroacetic acid should be stored in an acid cabinet away from other classes of compounds. Because of its high vapor pressure, fumes of trifluoroacetic acid can destroy labels on other bottles if the container is not tightly sealed.

Purification Methods

The purification of trifluoroacetic acid, reported in earlier editions of this work, by refluxing over KMnO4 for 24hours and slowly distilling has resulted in very SERIOUS EXPLOSIONS on various occasions, but not always. This apparently depends on the source and/or age of the acid. The method is NOT RECOMMENDED. Water can be removed by adding trifluoroacetic anhydride (0.05%, to diminish water content) and distilling. [Conway & Novak J Phys Chem 81 1459 1977]. It can be refluxed and distilled from P2O5. It is further purified by fractional crystallisation by partial freezing and again distilled. Highly TOXIC vapour. Work in an efficient fume hood. [Beilstein 2 IV 458.]

비 호환성

Mixing trifluoroacetic acid and water evolves considerable heat.

폐기물 처리

Trifluoroacetic acid and waste material containing this substance should be placed in an appropriate container, clearly labeled, and handled according to your institution's waste disposal guidelines.

트리플루오로아세트 산 준비 용품 및 원자재

원자재

준비 용품


트리플루오로아세트 산 공급 업체

글로벌( 394)공급 업체
공급자 전화 팩스 이메일 국가 제품 수 이점
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19918 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21726 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555
+86-021-57951555 jack.li@time-chemicals.com CHINA 1365 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
Zjartschem
+86-571-8723 8903 jocelynpan@zjarts.com
+86-571-87063838 jocelynpan@zjarts.com CHINA 997 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30004 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23978 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 sales@jushengtech.com CHINA 28236 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 8922 58

트리플루오로아세트 산 관련 검색:

Copyright 2019 © ChemicalBook. All rights reserved