Mozavaptan

Mozavaptan 구조식 이미지
카스 번호:
137975-06-5
상품명:
Mozavaptan
동의어(영문):
CS-134;OPC31260l;OPC 31260;MOZAVAPTAN;Mozavaptan USP/EP/BP;Mozavaptan (OPC-31260);N-(4-(5-(Dimethylamino);OPC-31260; OPC31260L; OPC 31260;-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl);5-(Dimethylamino)-1-[4-(2-methylbenzamido)benzoyl]-2,3,4,5-tetrahydro-1H-benzazepine
CBNumber:
CB51388577
분자식:
C27H29N3O2
포뮬러 무게:
427.54
MOL 파일:
137975-06-5.mol

Mozavaptan 속성

녹는점
213 - 217°C
끓는 점
543.0±50.0 °C(Predicted)
밀도
1.21±0.1 g/cm3(Predicted)
저장 조건
Sealed in dry,Room Temperature
용해도
클로로포름(약간 용해됨), DMSO(약간 용해됨), 메탄올(약간 용해됨)
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
13.04±0.70(Predicted)
색상
흰색에서 황백색까지

안전

Mozavaptan C화학적 특성, 용도, 생산

개요

Mozavaptan is an oral vasopressin V2 antagonist that has been launched in Japan for inappropriate antidiuretic hormone secretion syndrome (IADHS), an affliction manifesting as hyponatremia. It joins another nonpeptidic benzazepine, conivaptan, which corrects sodium and water imbalance by blocking the renal V2 receptor resulting in enhanced diuresis, thereby effectively increasing serum sodium concentration. While conivaptan inhibits both V1 and V2 receptors, mozavaptan is significantly more selective for V2 (IC50 of 14nM vs. 1.2 mM for V1).

용도

Mozavaptan is a vasopressin-receptor antagonist. It is used in the treatment of congestive heart failure and hyponatremia.

Mozavaptan 준비 용품 및 원자재

원자재

준비 용품


Mozavaptan 공급 업체

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