L-Homocystine
|
|
L-Homocystine 속성
- 녹는점
- 281-284 °C (dec.)(lit.)
- 알파
- 77 º (c=1% in 1N HCl)
- 끓는 점
- 507.6±50.0 °C(Predicted)
- 밀도
- 1.443±0.06 g/cm3(Predicted)
- 저장 조건
- Keep in dark place,Inert atmosphere,Room temperature
- 용해도
- H2O : 5 mg/mL (18.63 mM; ultrasonic and adjust pH to 3 with H2O)DMSO : 1 mg/mL (3.73 mM; ultrasonic and adjust pH to 5 with HCl)
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 1.90±0.10(Predicted)
- BRN
- 1728583
- InChIKey
- ZTVZLYBCZNMWCF-WDSKDSINSA-N
- CAS 데이터베이스
- 626-72-2(CAS DataBase Reference)
안전
| 안전지침서 | 22-24/25 | ||
|---|---|---|---|
| WGK 독일 | 3 | ||
| HS 번호 | 29309090 |
L-Homocystine C화학적 특성, 용도, 생산
화학적 성질
L-homocysteine is an aliphatic amino acid with the molecular formula (C8H16N2O4S2). It is a white powder with an acidic taste and is easily soluble in water. It has limited solubility in ethanol. L-homocysteine has a sulfhydryl group on its side chain, which allows it to form disulfide bonds with other L-homocysteine residues in proteins. This feature contributes to the stable three-dimensional structure of proteins. As a result, L-homocysteine finds extensive applications in industries such as pharmaceuticals, food, feed, and cosmetics.용도
Increased levels lead to hyperhomocysteinemia; a cardiovascular risk factor in prediction of coronary heart disease as well as being associated with congenital birth defects, pregnancy complications and cancer.Synthesis
L-homoserine(626-72-2) is biosynthesized from L-aspartate, which is synthesized from oxaloacetate, a TCA cycle intermediate. Homoserine is activated through esterification to form the O-acetyl ester by the enzyme homoserine O-acetyltransferase. In certain organisms, including the yeast Saccharomyces cerevisiae and certain bacteria, hydrogen sulfide reacts with O-acetyl-L-homoserine, replacing the acetyl group and forming L-homocysteine.
Purification Methods
The acid (3g) is dissolved in freshly boiled H2O (30mL) under N2, cooled under N2 (all operations should be under N2), absolute EtOH (100mL) is added, the acid is filtered off, and a second crop is obtained by diluting the filtrate to 500mL with absolute EtOH, kept overnight in a refrigerator, filtered, washed with EtOH and dried in a vacuum. The D(R,R)-form has similar properties but is –ve in M HCl and +ve in H2O. [du Vigneaud & Patterson J Biol Chem 109 101 1935, du Vigneaud & Brown Biochemical Preparations 5 93, 95 1975, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2667-2670 1961, Beilstein 4 III 1643, 4 IV 3199, Koegel et al. J Am Chem Soc 77 5708 1955.]L-Homocystine 준비 용품 및 원자재
원자재
L-Homoserine
소듐아스파테이트
(S)-4-ACETOXY-2-AMINO-BUTYRIC ACID
homoserine O-acetyltransferase
황화 수소
RIBOMINUS(BACTERIA)
준비 용품
L-Homocystine 공급 업체
글로벌( 240)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2503 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 |
info@konochemical.com | China | 2995 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 47465 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 |
info@antaichem.com | CHINA | 9641 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 |
sale04@alfachem.cn | China | 12468 | 58 |
L-Homocystine 관련 검색:
감마-아미노-N-부티르 산 N-아세틸-L(+)-시스틴 L-(-)-시스틴 L-시스테인 이황화 셀레늄 3-인돌부틸산 부틸다이설파이드 디노르말포로필디술파이드
D-2-Aminobutyric acid
DL-Homocysteine
DL-2-AMINOBUTYRIC ACID
DL-3-Aminobutyric acid
Cyproterone acetate
DL-2-Aminobutyric acid
L(+)-2-Aminobutyric acid
3-CARBOXYPROPYL DISULFIDE
Methyl propyl disulfide
r-Amino Butryric Acid