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ABT 737

ABT 737 구조식 이미지
카스 번호:
852808-04-9
상품명:
ABT 737
동의어(영문):
ABT 737;ABT-737, >=98%;ABT737/ABT-737;Bcl-2 Inhibitor VI, ABT-737 - CAS 852808-04-9 - Calbiochem;4-{4-[(4'-Chlorobiphenyl-2-yl)Methyl]piperazin-1-yl}-N-[(4-{[(2R)-4-(diMethylaMino)-1-;BenzaMide, 4-[4-[(4'-chloro[1,1'-biphenyl]-2-yl)Methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(diMethylaMino)-1-[(phenylthio)Methyl]propyl]aMin;(R)-4-(4-((4'-chlorobiphenyl-2-yl)Methyl)piperazin-1-yl)-N-(4-(4-(diMethylaMino)-1-(phenylthio)butan-2-ylaMino)-3-nitrophenylsulfonyl)benzaMide;4-{4-[(4'-Chlorobiphenyl-2-yl)Methyl]piperazin-1-yl}-N-[(4-{[(2R)-4-(diMethylaMino)-1-(phenylsulfanyl)butan-2-yl]aMino}-3-nitrophenyl)sulfonyl]benzaMide;4-[4-[(4'-Chloro[1,1'-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nitrophenyl]sulfonyl]benzamide;BenzaMide, 4-[4-[(4'-chloro[1,1'-biphenyl]-2-yl)Methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(diMethylaMino)-1-[(phenylthio)Methyl]propyl]aMino]-3-nitrophenyl]sulfonyl]-
CBNumber:
CB51872885
분자식:
C42H45ClN6O5S2
포뮬러 무게:
813.43
MOL 파일:
852808-04-9.mol

ABT 737 속성

녹는점
152-154°C
저장 조건
-20°C Freezer
물리적 상태
Yellow solid

안전

HS 번호 29309090

ABT 737 C화학적 특성, 용도, 생산

화학적 성질

Yellow Solid

용도

ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w with EC50 of 78.7 nM, 30.3 nM and 197.8 nM, respectively.

용도

A selective inhibitor of BCL-2, in small cell lung cancer. ABT-737 induced dramatic regressions in tumors derived from some SCLC cell lines.

ABT 737 준비 용품 및 원자재

원자재

준비 용품


ABT 737 공급 업체

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