BEPHENIUM HYDROXYNAPHTHOATE

BEPHENIUM HYDROXYNAPHTHOATE 구조식 이미지
카스 번호:
3818-50-6
상품명:
BEPHENIUM HYDROXYNAPHTHOATE
동의어(영문):
Bephenium;BEPHENIUM HYDROXYNAPTHOATE;BEPHENIUM HYDROXYNAPHTHOATE;3-hydroxynaphthalene-2-carboxylate;Bephenium Hydroxynaphthoate (500 mg);BEPHENIUM HYDROXYNAPHTHOATE USP/EP/BP;Bephenium Hydroxynaphthoate (1065006);dimethyl-[2-(phenoxy)ethyl]-(phenylmethyl)azanium;Bephenium (hydroxynaphthoate),Inhibitor,Parasite,inhibit;BENZYLDIMETHYL[2-PHENOXYETHYL]-AMMONIUM 3-HYDROXYNAPHTHOATE
CBNumber:
CB5206454
분자식:
C28H29NO4
포뮬러 무게:
443.53
MOL 파일:
3818-50-6.mol

BEPHENIUM HYDROXYNAPHTHOATE 속성

녹는점
170-171°
저장 조건
Store at -20°C
용해도
≥ 20.85mg/mL in DMSO

안전

WGK 독일 3

BEPHENIUM HYDROXYNAPHTHOATE C화학적 특성, 용도, 생산

용도

antibacterial, antilepretic, antituberculosis

Indications

This drug exhibits antihelmintic action by acting as a cholinergic agonist, causing paralysis of the parasite musculature. This facilitates its removal from the intestines. It is used for treating ascariasis, ankylostomiasis, enterobiasis, trichostrongyliasis, and tricocefalosis. A single dose of bephenium heals from 80 to 100% of patients infected with A. duodenale. It is less effective with respect to N. americanus. Synonyms of this drug are aclopar and others.

Synthesis

Bephenium, 3-hydroxy-2-naphthoat benzyldimethyl(2-phenoxyethyl) ammonia (38.1.37), is made by reacting the sodium salt of 3-hydroxy-2-naphthoic acid with benzyldimethyl(2-phenoxyethyl)ammonia chloride (38.1.36). This is in turn made from benzyl chloride and N-(2-phenoxyethyl)dimethylamine (38.1.35), which is synthesized by reacting sodium phenolate with 2-dimethylaminoethylchloride.

Synthesis_3818-50-6

BEPHENIUM HYDROXYNAPHTHOATE 준비 용품 및 원자재

원자재

준비 용품


BEPHENIUM HYDROXYNAPHTHOATE 공급 업체

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