캠페롤
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캠페롤 속성
- 녹는점
- 276°C
- 끓는 점
- 348.61°C (rough estimate)
- 밀도
- 1.2981 (rough estimate)
- 굴절률
- 1.4413 (estimate)
- 저장 조건
- 2-8°C
- 용해도
- 에탄올: 20mg/mL
- 산도 계수 (pKa)
- 6.34±0.40(Predicted)
- 물리적 상태
- 가루
- 색상 색인 번호
- 75640
- 색상
- 노란색
- Merck
- 14,5274
- BRN
- 304401
- 안정성
- 솔루션이 불안정함
- InChIKey
- IYRMWMYZSQPJKC-UHFFFAOYSA-N
- LogP
- 2.685 (est)
- CAS 데이터베이스
- 520-18-3(CAS DataBase Reference)
- IARC
- 3 (Vol. 31, Sup 7) 1987
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi,T | ||
---|---|---|---|
위험 카페고리 넘버 | 36/37/38-68-25 | ||
안전지침서 | 26-36-45-36/37-36/37/38-22 | ||
유엔번호(UN No.) | 2811 | ||
WGK 독일 | - | ||
RTECS 번호 | LK9275200 | ||
F 고인화성물질 | 8-10-23 | ||
HS 번호 | 29329990 | ||
유해 물질 데이터 | 520-18-3(Hazardous Substances Data) |
캠페롤 C화학적 특성, 용도, 생산
화학적 성질
Yellow Solid용도
Kaempferol, is used as an inhibitor of Fatty Acid Synthase, Cox-1 activity, and Topo I. It also Induces caspase-9-mediated apoptosis in a variety of cancer cell lines via downregulation of polo-like kinase 1 (PLK1) expression. Exhibits antioxidant activity and attenuates osteoclastic bone reabsorption in vitro. Also blocks EGF-induced histone H3Ser10 phosphorylation in mouse epidermal JB6 C141 cells.일반 설명
Kaempferol is a polyphenolic antioxidant abundantly present in vegetables and fruits. It has a diphenylpropane structure. In many plants, it is present as a glycosidic form namely, kaempferol-3-O-glucoside.생물학적 활성
Naturally occurring flavonoid found in Gingko biloba and red wines that activates the mitochondrial Ca 2+ uniporter (EC 50 = 7 μ M). Induces caspase-9-mediated apoptosis in a variety of cancer cell lines via downregulation of polo-like kinase 1 (PLK1) expression. Exhibits antioxidant activity and attenuates osteoclastic bone reabsorption in vitro .Anticancer Research
Kaempferol is one of the secondary metabolites found in some plants, plant-derivedfoods, and traditional medicines. It is a flavonoid compound obtained from someedible plants including grapes, tea, strawberries, broccoli, tomato, cabbage, leek,kale, endive, and beans. It inhibits growth and migration of pancreatic cancer cellsby acting on proto-oncogene tyrosine kinase (Src), ERK1/2, and AKT pathways(Singh et al. 2016a). It is being investigated in pancreatic and lung cancers toevaluate its antiangiogenic, anticancer, and radical scavenging activities. It showsmoderate cytostatic activity in PC3, HeLa, and K562 human cancer cells. It isidentified as aryl hydrocarbon receptor antagonist and acts against ABCG2 (ATP-bindingcassette subfamily G member 2)-mediated multidrug resistance bypreventing the ABCG2 upregulation in esophageal carcinoma. It induces theapoptosis of ovarian cancer cell by activating p53 in intrinsic pathway mechanism.It is an inhibitor of breast cancer resistance protein (BCRP), quinine reductase-2,and a substrate of BCRP (Calderon-Montano et al. 2011; Wang et al. 2012).캠페롤 준비 용품 및 원자재
원자재
준비 용품
캠페롤 공급 업체
글로벌( 585)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Shaanxi LonierHerb Bio Technology Co Ltd | +86-86-+86-86-029-87551862 +8617702909819 |
sales006@ingredients-lonier.com | China | 2605 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 |
1022@dideu.com | China | 3878 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 |
sales1@chuanghaibio.com | China | 5882 | 58 |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2503 | 58 |
Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 |
lisa@kingfinertech.com | China | 2990 | 58 |
Wuhan Haorong Biotechnology Co.,ltd | +86-18565342920; +8618565342920 |
sales@chembj.net | China | 289 | 58 |
Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 |
qinhe02@xaltbio.com | China | 1000 | 58 |
Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 |
admin@guyunchem.com | China | 616 | 58 |
Chongqing Zhihe Biopharmaceutical Co., Ltd. | +8618580541567 |
sales@zhswyy.com | China | 303 | 58 |
BINBO BIOLOGICAL CO.,LTD | +8618629063126 |
info@binbobiological.com | China | 346 | 58 |
캠페롤 관련 검색:
이소플라본 플라본 크리신 케르세틴 디하이드레이트 바이칼린 아스트라갈린 케르세틴 캠퍼롤
ARTEMISININ
7-HYDROXYFLAVONE
Hydroxy silicone oil
KAEMPFERITRIN
KAEMPFEROL-3-O-RUTINOSIDE,KAEMPFEROL-3-RUTINOSIDE
Rotundine
Sophoricoside
Kaempferol 3-neohesperidoside
7-[[2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-3,5-dihydroxy-2-(4-hydroxyphenyl)-4H-benzopyran-4-one
kaempferol-3-O-galactoside