Egrifta

Egrifta C화학적 특성, 용도, 생산

개요

Tesamorelin acetate is an analog of growth hormone-releasing hormone (GHRH) that was approved in the United States in 2010 for treatment of lipodystrophy in HIV patients. Tesomorelin is an analog of GHRH. GHRH stimulates the synthesis and release of GH. In the pituitary, GH is secreted in a pulsatile manner. GH control is regulated by somatostatin and the negative feedback regulator, IGF-1. Direct administration of GH to patients with lipodystrophy decreases VAT but has associated side effects such as fluid retention and joint swelling. Because of the side effects associated with direct GH administration, GHRH represents a attractive mechanism for increasing GH levels. Tesomorelin is an analog of GHRH in which the N-terminal amino acid, Tyr, is amidated with a trans-3-hexenoyl group. Capping of the N-terminus protects GHRH from cleavage by DPP-4. Tesomorelin demonstrates enhanced stability compared with GHRH in animal models.

Originator

Theratechnologies (Canada)

용도

Egrifta (Tesamorelin) is used to reduce excess abdominal fat in HIV-infected lipodystrophy patients. Some HIV medicines cause this side effect (increased fat in the upper back and abdomen and decreased fat in the arms and legs.) Tesamorelin works by making the body produce more growth hormone. This medicine should not be used for weight loss.

상표명

Egrifta

Egrifta 준비 용품 및 원자재

원자재

준비 용품

Egrifta 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Sichuan Tai Hui Biotechnology Co., Ltd	+86-18224031330 +86-18081096520	404435307@qq.com	China	23	58
Henan Tengmao Chemical Technology Co. LTD	+8615238638457	salesvip2@hntmhg.com	China	415	58
Zhejiang Hangyu API Co., Ltd	+8617531972939	anna@api-made.com	China	2944	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12453	58
Hebei Xinsheng New Material Technology Co., LTD.	+86-16632316109	xinshengkeji@xsmaterial.com	China	1100	58
Hebei Anlijie Biotechnology Co., Ltd	+8619031013551	ably@aljbio.com	China	177	58
Qingdao Sigma Chemical Co., Ltd	+8618661891880	info@sigmachemical.com.cn	China	50	58
zhuzhou dingcheng meihei comestic co.,ltd	+undefined18873369619	dingchengbusiness8@163.com	China	241	58
.GZ HONESTCHEM CO.,LTD	+86-15013270415	honestchemical@foxmail.com	China	247	58
Shanghai Longyu Biotechnology Co., Ltd.	+8615821988213	info@longyupharma.com	China	2531	58