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NVP-LDE225

NVP-LDE225 구조식 이미지
카스 번호:
956697-53-3
상품명:
NVP-LDE225
동의어(영문):
CS-65;LDE225;AZP-577;Sonidegib;NVP-LDE225;Erismodegib;Sonidegib HCL;SONIDEGIB(LDE225);LDE225 (NVP-LDE225);NVP-LDE225,Sonidegib
CBNumber:
CB52515129
분자식:
C26H26F3N3O3
포뮬러 무게:
485.5
MOL 파일:
956697-53-3.mol

NVP-LDE225 속성

끓는 점
544.5±50.0 °C(Predicted)
밀도
1.255
물리적 상태
White solid.
산도 계수 (pKa)
9.53±0.70(Predicted)

안전

NVP-LDE225 C화학적 특성, 용도, 생산

용도

A potent, selective and orally bioavailable Smoothened (SMO) antagonist; it inhibits hedgehog (Hh) signaling pathway via antagonism of the Smoothened receptor (SMO). Antineoplastic.

용도

A potent, selective and orally bioavailable Smoothened (SMO) antagonist; it inhibits hedgehog (Hh) signaling pathway via antagonism of the Smoothened receptor (SMO). Antineoplastic. Potent Hedgehog inhibitor.

정의

ChEBI: A member of the classo of biphenyls that is the amide obtained by formal condensation of the carboxy group of 2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxylic acid with the amino group of 6-(2,6-dimethylmorpholin-4-yl)pyridin-3-amine. Used (as it phosphate salt) for treatment of locally advanced basal cell carcinoma.

NVP-LDE225 준비 용품 및 원자재

원자재

준비 용품


NVP-LDE225 공급 업체

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