(3S,5R)-Rosuvastatin
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(3S,5R)-Rosuvastatin 속성
- 끓는 점
- 745.6±70.0 °C(Predicted)
- 밀도
- 1.368±0.06 g/cm3(Predicted)
- 용해도
- soluble in Methanol, Water
- 산도 계수 (pKa)
- 4.25±0.10(Predicted)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 황백색에서 연한 노란색
- 안정성
- 흡습성
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
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| 유해·위험 문구: |
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| 예방조치문구: |
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(3S,5R)-Rosuvastatin C화학적 특성, 용도, 생산
개요
Rosuvastatin is an HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.용도
(3S,5R,6E)-Rosuvastatin is an isomer of Rosuvastatin(R700500), an impurity which acts as a selective, competitive HMG-CoA reductase inhibitor.생물학적 활성
(3S,5R)-Rosuvastatin is the (3S,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM. Rosuvastatin potently blocks human ether-a-go-go related gene (hERG) current with an IC50 of 195 nM. Rosuvastatin reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin is very effective in lowering low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.(3S,5R)-Rosuvastatin 준비 용품 및 원자재
원자재
준비 용품
(3S,5R)-Rosuvastatin 공급 업체
글로벌( 72)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |
| Standardpharm Co. Ltd. | 86-714-3992388 |
overseasales1@yongstandards.com | United States | 14336 | 58 |
| BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 |
info@antaichem.com | CHINA | 9641 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; |
laboratory@coreychem.com | China | 30255 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 |
eric@witopchemical.com | China | 23556 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 |
info@finetechnology-ind.com | China | 9702 | 58 |
| CR Corporation Lomited | |
fred.wen@crcorporation.cn | CHINA | 12069 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 |
dj@sgtlifesciences.com | China | 12382 | 58 |
(3S,5R)-Rosuvastatin 관련 검색:
Rosuvastatin EP Impurity E (Calcium Salt)
Rosuvastatin EP impurity H
Rosuvastatin ethyl ester
3-Oxo Rosuvastatin SodiuM Salt
4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-n-methylsulfonyl)amino]pyrimidine-5-yl-methanol
tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate
Rosuvastatin methyl ester
N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide
Rosuvastatin EP impurity A
Rosuvastatin IsoaMy Ester
Rosuvastatin Anhydro Lactone
Rosuvastatin IMpurity (5-Oxo Rosuvastatin tert-Butyl Ester)
(3S,5R)-Rosuvastatin Methyl Ester
Rosuvastatin
N-DESMETHYL ROSUVASTATIN-D3
(3R,5R)-Rosuvastatin
Rosuvastatin Impurity 14
Pitavastatin Impurity 8