하이드록시아이소류신
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하이드록시아이소류신 속성
- 녹는점
- 223-224℃
- 끓는 점
- 331.6±32.0 °C(Predicted)
- 밀도
- 1.181±0.06 g/cm3 (20 ºC 760 Torr)
- 인화점
- 147℃
- 저장 조건
- Keep in dark place,Inert atmosphere,2-8°C
- 용해도
- 메탄올(약간 용해됨), 물(약간 용해됨)
- 산도 계수 (pKa)
- 2.41±0.25(Predicted)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 흰색에서 황백색까지
- optical activity
- [α]/D +32.5±2.0°, c = 1 in H2O
- BRN
- 4128096
- InChI
- InChI=1S/C6H13NO3/c1-3(4(2)8)5(7)6(9)10/h3-5,8H,7H2,1-2H3,(H,9,10)/t3-,4-,5-/m0/s1
- InChIKey
- OSCCDBFHNMXNME-YUPRTTJUSA-N
- SMILES
- C(O)(=O)[C@@H](N)[C@@H](C)[C@H](C)O
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
하이드록시아이소류신 C화학적 특성, 용도, 생산
개요
4-Hydroxyisoleucine is an amino acid that has been found in fenugreek (T. foenum graecum) seeds and has antidiabetic activity. It increases glucose-stimulated insulin release from isolated rat islets and isolated perfused rat pancreas when used at a concentration of 200 μM. In vivo, 4-hydroxyisoleucine increases PI3K activity in muscle and liver in rats when administered at a dose of 18 mg/kg and in muscle in a rat model of type 2 diabetes induced by nicotinamide and streptozotocin (STZ; ) when administered at 25 mg/kg. 4-Hydroxyisoleucine (50 mg/kg per day for four weeks) decreases plasma glucose, triglyceride, LDL, HDL, and cholesterol levels in an STZ-induced rat model of type 1 diabetes.출처
4-hydroxyisoleucine has been extracted and purified from fenugreek seeds, which are known in traditional medicine for their antidiabetic properties.용도
(4S)-4-Hydroxy-L-isoleucine is 4S isomer of 4-Hydroxyisoleucine, which is used as a treatment for type II diabetes.정의
ChEBI: An L-isoleucine derivative that is L-isoleucine bearing a (4S)-hydroxy substituent.생물학적 활성
4-Hydroxyisoleucine increases glucose-induced insulin release, in the concentration range of 100 micromol/l to 1 mmol/l, through a direct effect on isolated islets of Langerhans from both rats and humans.하이드록시아이소류신 준비 용품 및 원자재
원자재
준비 용품
하이드록시아이소류신 공급 업체
글로벌( 183)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| ChiRial Biomaterial Co Ltd | +8619951673840 |
cero.xia@chirial.com | China | 156 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5993 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15371 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21695 | 55 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Shaanxi Yikanglong Biotechnology Co., Ltd. | 17791478691 |
yklbiotech@163.com | CHINA | 296 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 |
figo.gao@foxmail.com | China | 6992 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 |
sales@dolonchem.com | CHINA | 2972 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 |
info@konochemical.com | China | 2995 | 58 |
하이드록시아이소류신 관련 검색:
트리메틸클로로실란 L-(-)-루신 L-글루타민 칼륨 피로인산염 L-(+)-아이소루신 진저롤 망고스틴
GAMBOGIC ACID
Cryptochlorogenic acid
L-Hydroxyproline
DL-2-Aminobutyric acid
Isochlorogenic acid A
Isochlorogenic Acid B
Calcium 3-methyl-2-oxovalerate
Common Fenugreek Seed P.E.
(2S,4R)-N-Boc-4-hydroxy-3,3-dimethylpyrrolidine-2-carboxylic acid
4-HYDROXYISOLEUCINE
4-Hydroxyisoleucine